Suppr超能文献

卫星细胞在骨骼肌再生中的作用——运动和年龄的影响。

The Role of Satellite Cells in Skeletal Muscle Regeneration-The Effect of Exercise and Age.

作者信息

Kaczmarek Agnieszka, Kaczmarek Mateusz, Ciałowicz Maria, Clemente Filipe Manuel, Wolański Paweł, Badicu Georgian, Murawska-Ciałowicz Eugenia

机构信息

Department of Physiology and Biochemistry, University School of Physical Education, 51-612 Wroclaw, Poland.

Gynecology and Obstetrics Department, St. Hedwig's of Silesia Hospital, 55-100 Trzebnica, Poland.

出版信息

Biology (Basel). 2021 Oct 18;10(10):1056. doi: 10.3390/biology10101056.

Abstract

The population of satellite cells (mSCs) is highly diversified. The cells comprising it differ in their ability to regenerate their own population and differentiate, as well as in the properties they exhibit. The heterogeneity of this group of cells is evidenced by multiple differentiating markers that enable their recognition, classification, labeling, and characterization. One of the main tasks of satellite cells is skeletal muscle regeneration. Myofibers are often damaged during vigorous exercise in people who participate in sports activities. The number of satellite cells and the speed of the regeneration processes that depend on them affect the time structure of an athlete's training. This process depends on inflammatory cells. The multitude of reactions and pathways that occur during the regeneration process results in the participation and control of many factors that are activated and secreted during muscle fiber damage and at different stages of its regeneration. However, not all of them are well understood yet. This paper presents the current state of knowledge on satellite cell-dependent skeletal muscle regeneration. Studies describing the effects of various forms of exercise and age on this process were reviewed.

摘要

卫星细胞(mSCs)群体高度多样化。构成该群体的细胞在自我增殖能力、分化能力以及所表现出的特性方面存在差异。这组细胞的异质性通过多种分化标志物得以证明,这些标志物能够实现对它们的识别、分类、标记和表征。卫星细胞的主要任务之一是骨骼肌再生。在参与体育活动的人群进行剧烈运动时,肌纤维常常会受损。卫星细胞的数量以及依赖于它们的再生过程的速度会影响运动员训练的时间安排。这个过程依赖于炎症细胞。再生过程中发生的众多反应和途径导致许多在肌纤维损伤及其再生的不同阶段被激活和分泌的因素参与其中并受到调控。然而,目前并非所有这些因素都已被充分理解。本文介绍了关于卫星细胞依赖性骨骼肌再生的当前知识状态。对描述各种运动形式和年龄对该过程影响的研究进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ef/8533525/731df3934d1d/biology-10-01056-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验