Verma Swati, Mehta Falguni, Mishra SukhDev, Mohamed Roshan Noor, Parekh Harshik Kumar A, Sokhi Ramandeep Kaur, Nagarajappa Anil Kumar, Alam Mohammad Khursheed
Division of Orthodontics and Dentofacial Deformities, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi 110029, India.
Department of Orthodontics and Dentofacial Orthopaedics, Government Dental College and Hospital, Ahmedabad 380016, Gujarat, India.
Children (Basel). 2021 Oct 6;8(10):893. doi: 10.3390/children8100893.
The oro-facial morphology is greatly affected in neonates with a cleft lip and palate. The initial evaluation of neonate's body and maxillary arch dimensions is important for treatment planning and predicting growth in cleft patients. The objective of this study was comparative evaluation of the anthropometric and physiologic parameters of cleft and non-cleft neonates in a hospital-based set up. This cross sectional study was conducted on 88 cleft and non-cleft neonates ( = 44 in each group) aged between 0 and 30 days after obtaining approval from the institutional ethics committee and positive written informed consent from their parents. Neonates' body weight, body length, head length, head circumference, and maxillary arch dimensions were measured. Maxillary arch dimensions were measured on dental casts with digital sliding calipers. Statistical analyses performed using the independent -test and one-way ANOVA analysis were followed by Bonferroni correction for post-hoc comparison. The results showed statistically significant differences in birth weight ( < 0.0001), head length ( < 0.01), head circumference ( < 0.007), and maxillary arch dimensions ( < 0.0001) between cleft and non-cleft neonates. These findings suggest that cleft neonates had significant anthropometric and physiologic variations than non-cleft neonates.
唇腭裂新生儿的口面部形态受到极大影响。对新生儿身体和上颌弓尺寸进行初步评估对于腭裂患者的治疗规划和生长预测很重要。本研究的目的是在医院环境中对唇腭裂新生儿和非唇腭裂新生儿的人体测量学和生理学参数进行比较评估。在获得机构伦理委员会批准并得到其父母的书面知情同意后,对88名年龄在0至30天之间的唇腭裂和非唇腭裂新生儿(每组 = 44名)进行了这项横断面研究。测量了新生儿的体重、身长、头长、头围和上颌弓尺寸。使用数字游标卡尺在石膏模型上测量上颌弓尺寸。使用独立样本t检验和单因素方差分析进行统计分析,随后进行Bonferroni校正以进行事后比较。结果显示,唇腭裂新生儿和非唇腭裂新生儿在出生体重(P < 0.0001)、头长(P < 0.01)、头围(P < 0.007)和上颌弓尺寸(P < 0.0001)方面存在统计学上的显著差异。这些发现表明,唇腭裂新生儿与非唇腭裂新生儿相比,在人体测量学和生理学方面存在显著差异。