Yeoh Zhi Han, Bajel Ashish, Wei Andrew H
Department of Clinical Haematology, Peter MacCallum Cancer Centre & The Royal Melbourne Hospital, Melbourne, VIC 3000, Australia.
The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC 3000, Australia.
J Pers Med. 2021 Oct 3;11(10):1003. doi: 10.3390/jpm11101003.
The better understanding of the genomic landscape in acute myeloid leukaemia (AML) has progressively paved the way for precision medicine in AML. There is a growing number of drugs with novel mechanisms of action and unique side-effect profiles. This review examines the impact of evolving novel therapies on survival in AML and the challenges that ensue.
对急性髓系白血病(AML)基因组格局的深入了解逐渐为AML的精准医学铺平了道路。具有新作用机制和独特副作用特征的药物越来越多。本综述探讨了不断发展的新疗法对AML患者生存的影响以及随之而来的挑战。