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新药给急性髓系白血病带来新挑战:简要综述

New Drugs Bringing New Challenges to AML: A Brief Review.

作者信息

Yeoh Zhi Han, Bajel Ashish, Wei Andrew H

机构信息

Department of Clinical Haematology, Peter MacCallum Cancer Centre & The Royal Melbourne Hospital, Melbourne, VIC 3000, Australia.

The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC 3000, Australia.

出版信息

J Pers Med. 2021 Oct 3;11(10):1003. doi: 10.3390/jpm11101003.

Abstract

The better understanding of the genomic landscape in acute myeloid leukaemia (AML) has progressively paved the way for precision medicine in AML. There is a growing number of drugs with novel mechanisms of action and unique side-effect profiles. This review examines the impact of evolving novel therapies on survival in AML and the challenges that ensue.

摘要

对急性髓系白血病(AML)基因组格局的深入了解逐渐为AML的精准医学铺平了道路。具有新作用机制和独特副作用特征的药物越来越多。本综述探讨了不断发展的新疗法对AML患者生存的影响以及随之而来的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4037/8537004/85e27b21e602/jpm-11-01003-g001.jpg

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