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社区居住人群中腰椎狭窄症症状在六年期间的变化。

The Change of Lumbar Spinal Stenosis Symptoms over a Six-Year Period in Community-Dwelling People.

机构信息

Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, 1 Hikari-gaoka, Fukushima City 960-1295, Japan.

出版信息

Medicina (Kaunas). 2021 Oct 16;57(10):1116. doi: 10.3390/medicina57101116.

Abstract

: The high prevalence of lumbar spinal stenosis (LSS) and its negative impact on quality of life in the elderly is well known. However, the longitudinal time course of LSS symptoms remains unclear. The purpose of this study was to clarify the longitudinal time course and associated factors of LSS symptoms over a period of six years in a community. : This study was conducted with data prospectively collected in 2004 and 2010 under a retrospective design. In 2004, 1578 subjects (age range: 40 to 79 years) were interviewed on LSS symptoms using a specially designed and validated questionnaire. In 2010, a follow-up study was performed by mail, to which 789 subjects of the 2004 study population responded. Considering that the presence of osteoarthritis (OA) of the knee or hip may influence the participants' answers in the questionnaire, analysis was performed in all 789 subjects with and 513 subjects without either knee or hip OA. Changes in LSS symptoms between the initial and the 6-year survey were investigated. Multiple logistic regression analysis was used for detecting the risk factors for LSS symptom presence at the six-year follow-up. : 1. At the six-year follow-up, more than half of the subjects who showed LSS symptoms at the initial analysis became LSS-negative, and 12-15% of those who were LSS-negative became LSS-positive. 2. From the multiple logistic regression analysis, a lower Roland-Morris Disability Questionnaire (RDQ) score and a positive LSS symptom at the initial analysis were detected as predictive factors of the presence of LSS symptoms at the six-year follow-up in the total number of subjects, as well as just in those who did not have either knee or hip OA. : More than half of the subjects who were LSS-positive at their initial assessment still experienced improvement in their symptoms even after 6 years. This means that both LSS symptoms and their time course vary from person to person. Predictive factors for the presence of LSS symptoms during the six-year follow-up period were RDQ score and positive LSS symptoms.

摘要

: 腰椎管狭窄症(LSS)的高发率及其对老年人生活质量的负面影响是众所周知的。然而,LSS 症状的纵向时间进程仍不清楚。本研究旨在阐明在社区中,LSS 症状在六年期间的纵向时间进程和相关因素。: 本研究采用前瞻性设计,于 2004 年和 2010 年收集数据。2004 年,对 1578 名受试者(年龄范围:40-79 岁)采用专门设计并验证的问卷进行 LSS 症状访谈。2010 年,通过邮件进行了随访研究,2004 年研究人群中有 789 名受试者做出了回应。考虑到膝关节或髋关节的骨关节炎(OA)可能会影响参与者在问卷中的回答,因此在所有 789 名受试者以及 513 名没有膝关节或髋关节 OA 的受试者中进行了分析。研究了初始调查和 6 年调查之间 LSS 症状的变化。采用多变量逻辑回归分析检测 6 年随访时 LSS 症状存在的危险因素。: 1. 在 6 年随访时,在初始分析中出现 LSS 症状的受试者中,有一半以上变为 LSS 阴性,而在初始分析中为 LSS 阴性的受试者中,有 12-15%变为 LSS 阳性。2. 多变量逻辑回归分析显示,在总人群中,以及在没有膝关节或髋关节 OA 的人群中,Roland-Morris 残疾问卷(RDQ)评分较低和初始分析中出现 LSS 症状均为 6 年随访时存在 LSS 症状的预测因素。: 在初始评估中为 LSS 阳性的受试者中,有一半以上在 6 年后仍出现症状改善。这意味着 LSS 症状及其时间进程因人而异。6 年随访期间存在 LSS 症状的预测因素是 RDQ 评分和阳性 LSS 症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64c1/8537511/f36ed9d37b5a/medicina-57-01116-g001.jpg

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