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植物化学、民族药理学用途、生物学活性和治疗应用的 L.:全面综述。

Phytochemistry, Ethnopharmacological Uses, Biological Activities, and Therapeutic Applications of L.: A Comprehensive Review.

机构信息

Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.

Department of Prescriptionology, College of Korean Medicine, Kyung Hee University, 26, Kyunghee dae-ro, Dongdaemun-gu, Seoul 02447, Korea.

出版信息

Molecules. 2021 Oct 15;26(20):6252. doi: 10.3390/molecules26206252.

Abstract

L., of the Leguminosae family, is used as a diuretic, laxative, tonic, purgative, and natural remedy for treating headache, dizziness, constipation, tophobia, and lacrimation and for improving eyesight. It is commonly used in tea in Korea. Various anthraquinone derivatives make up its main chemical constituents: emodin, chrysophanol, physcion, obtusifolin, obtusin, au rantio-obtusin, chryso-obtusin, alaternin, questin, aloe-emodin, gluco-aurantio-obtusin, gluco-obtusifolin, naphthopyrone glycosides, toralactone-9-β-gentiobioside, toralactone gentiobioside, and cassiaside. .  . possesses a wide range of pharmacological properties (e.g., antidiabetic, antimicrobial, anti-inflammatory, hepatoprotective, and neuroprotective properties) and may be used to treat Alzheimer's disease, Parkinson's disease, and cancer. In addition, . L. contributes to histamine release and antiplatelet aggregation. This review summarizes the botanical, phytochemical, and pharmacological features of . and its therapeutic uses.

摘要

L.,属于豆科植物,被用作利尿剂、泻药、滋补剂、泻药和天然药物,用于治疗头痛、头晕、便秘、痛风、流泪和改善视力。它在韩国常用于泡茶。其主要化学成分包括各种蒽醌衍生物:大黄素、大黄酚、大黄酸、钝叶决明素、钝叶决明苷、橙色钝叶决明苷、金黄决明苷、白杨素、大波斯菊苷、芦荟大黄素、葡萄糖橙皮苷、葡萄糖钝叶决明苷、萘并吡喃酮糖苷、托拉内酯-9-β-龙胆二糖苷、托拉内酯龙胆二糖苷和决明子苷。。 。具有广泛的药理作用(如抗糖尿病、抗菌、抗炎、保肝和神经保护作用),可用于治疗阿尔茨海默病、帕金森病和癌症。此外,。L. 有助于组胺释放和抗血小板聚集。本综述总结了。和其治疗用途的植物学、植物化学和药理学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e618/8538231/de1f5d51b967/molecules-26-06252-g001a.jpg

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