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来自植物源的血小板聚集潜在抑制剂,V. 决明子种子中的蒽醌类化合物及相关化合物。

Potential inhibitors of platelet aggregation from plant sources, V. Anthraquinones from seeds of Cassia obtusifolia and related compounds.

作者信息

Yun-Choi H S, Kim J H, Takido M

机构信息

Natural Products Research Institute, Seoul National University, Korea.

出版信息

J Nat Prod. 1990 May-Jun;53(3):630-3. doi: 10.1021/np50069a014.

DOI:10.1021/np50069a014
PMID:2213033
Abstract

Three anthraquinone glycosides, gluco-obtusifolin [11], gluco-chryso-obtusin [15], and gluco-aurantioobtusin [13], were found to be platelet anti-aggregatory constituents of seeds of Cassia obtusifolia. Various other anthraquinone analogues were also tested, and their structure-activity relationships are discussed.

摘要

三种蒽醌糖苷,即葡萄糖钝叶决明素[11]、葡萄糖金决明素[15]和葡萄糖橙钝叶决明素[13],被发现是决明子种子中具有抗血小板聚集作用的成分。还测试了其他多种蒽醌类似物,并讨论了它们的构效关系。

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