热休克反应在自身免疫中的病理生理学作用：文献综述。
The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review.
机构信息
Department of Nephrology, Friedrich Alexander University, 91054 Erlangen, Germany.
Department of Nephrology, University of Crete, 71500 Heraklion, Greece.
出版信息
Cells. 2021 Oct 1;10(10):2626. doi: 10.3390/cells10102626.
Abstract
Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses. This review focuses on outlining the stimulatory as well as the inhibitory effects of heat-shock proteins 27, 40, 70, 65, 60, and 90 in experimental and clinical autoimmune settings.
摘要
在过去的二十年中，越来越多的证据表明热休克蛋白可能对免疫系统产生不同的影响。它们可以引发或减轻免疫反应。这篇综述重点概述了热休克蛋白 27、40、70、65、60 和 90 在实验和临床自身免疫环境中的刺激和抑制作用。
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