Department of Cell Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, 14476 Potsdam-Golm, Germany.
Cells. 2021 Oct 5;10(10):2657. doi: 10.3390/cells10102657.
The centrosome of amoebae contains no centrioles and consists of a cylindrical layered core structure surrounded by a corona harboring microtubule-nucleating γ-tubulin complexes. It is the major centrosomal model beyond animals and yeasts. Proteomics, protein interaction studies by BioID and superresolution microscopy methods led to considerable progress in our understanding of the composition, structure and function of this centrosome type. We discuss all currently known components of the centrosome in comparison to other centrosomes of animals and yeasts.
类星体的中心体不含中心粒,由一个圆柱形分层核心结构组成,周围是一个冠,其中含有微管起始 γ-微管蛋白复合物。它是动物和酵母之外的主要中心体模型。蛋白质组学、BioID 蛋白相互作用研究和超分辨率显微镜方法使我们对这种中心体类型的组成、结构和功能有了相当大的了解。我们将讨论所有目前已知的中心体成分与动物和酵母的其他中心体进行比较。