Department of Agricultural Chemistry, Faculty of Agriculture, Minia University, Minia, Egypt.
Environ Sci Pollut Res Int. 2022 Mar;29(12):17932-17942. doi: 10.1007/s11356-021-17060-x. Epub 2021 Oct 22.
Electromagnetic fields (EMFs) are common in our everyday lives. They have many origins and severe effects on individuals and environments where they inflict a great deal of health and psychological harm. The current study investigated the impact of high voltage (H.V.) EMF 5.4 kV/m for 2 and 4 h per day with a frequency equal to 50 Hz alternating current (AC) on body weight (b.wt), blood indices, and certain liver enzymes of albino rats after 25 days of exposure to the electromagnetic field. This work focuses on the therapeutic action of methanol extract of Rosmarinus officinalis (R. officinalis) leaves at a dose (5 mg/kg b. wt) against harmful EMF-induced effects. The findings showed that electromagnetic field exposure induced a substantial decrease in red blood cells (RBC), haemoglobin concentration (Hb), and catalase activity (CAT). Although white blood cells (WBCs), aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, urea, creatinine, uric acid, and malondialdehyde (MDA) levels have increased significantly under EMF treatment. Treatment with R. officinalis showed attenuation in these parameters that were induced in rats exposed to H.V. These findings were followed by the histopathological analysis of the liver in the observations. Finally, we conclude that R. officinalis leaves extract offered substantial protection against H.V-induced liver damage and can be applied in drug production.
电磁场(EMF)在我们的日常生活中很常见。它们有许多来源,对个体和环境都有严重影响,会造成很大的健康和心理伤害。本研究调查了每天暴露于 5.4kV/m 的高压(H.V.)电磁场 2 小时和 4 小时,频率为 50Hz 交流电(AC)对 25 天后的白鼠体重(b.wt)、血液指数和某些肝脏酶的影响。这项工作重点研究了迷迭香(R. officinalis)甲醇提取物在 5mg/kg b.wt 剂量下对有害 EMF 诱导效应的治疗作用。研究结果表明,电磁场暴露会导致红细胞(RBC)、血红蛋白浓度(Hb)和过氧化氢酶活性(CAT)显著下降。尽管在 EMF 治疗下白细胞(WBC)、天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、总胆红素、尿素、肌酐、尿酸和丙二醛(MDA)水平显著升高。用迷迭香处理可以减轻这些在 H.V.照射下诱导的参数。这些发现随后通过观察对肝脏的组织病理学分析得到证实。最后,我们得出结论,迷迭香叶提取物对 H.V.引起的肝损伤提供了实质性的保护,可以应用于药物生产。