Schuknecht Bernhard
Medical Radiological Institute, Bahnhofplatz 3, Zürich 8001, Switzerland.
Neuroimaging Clin N Am. 2021 Nov;31(4):473-483. doi: 10.1016/j.nic.2021.05.007.
Perineural extension is an increasingly recognized pathway of extension of cutaneous, mucosal, and salivary gland neoplasms associated with a severe adverse prognosis. Imaging identification is feasible by MR imaging 3-dimensional contrast-enhanced submillimetric sequences. The trigeminal nerve branches and facial nerve are the most commonly involved. PET with computed tomography may aid in the identification of the primary tumor location or recognition of recurrence, but only in conjunction with MR imaging does it achieve similar detection rates for perineural extension. Computed tomography scanning is an adjunct to MR imaging to increase specificity and for surgical treatment planning.
神经周围浸润是皮肤、黏膜及涎腺肿瘤越来越被认识到的一种浸润途径，与严重不良预后相关。通过磁共振成像三维对比增强亚毫米序列可行影像学识别。三叉神经分支和面神经是最常受累的部位。正电子发射断层显像（PET）联合计算机断层扫描（CT）有助于识别原发肿瘤位置或复发情况，但只有与磁共振成像联合使用时，其对神经周围浸润的检出率才与磁共振成像相似。CT扫描是磁共振成像的辅助手段，可提高特异性并用于手术治疗规划。
