Levy R, Har-El G, Segal K, Sidi J
Int J Pediatr Otorhinolaryngol. 1986 Nov;12(1):49-53. doi: 10.1016/s0165-5876(86)80056-8.
A case is presented of a 5.5-year-old girl admitted with acute mastoiditis and facial nerve palsy. The final diagnosis of leukemic infiltration of the mastoid bone, middle ear and VIIth cranial nerve was made only after surgery and histological examination. Similar cases described in the English literature are reviewed and treatment is discussed. Chemotherapy or combined chemo- and radiotherapy are the treatment of choice in known leukemic patients without symptoms of superimposed infection of the ear or the mastoid process. Surgical management is restricted to cases in which tissue for histological diagnosis is required or drainage of acute infection is needed.
本文报告一例5.5岁女童,因急性乳突炎和面神经麻痹入院。仅在手术后及组织学检查后才最终诊断为乳突骨、中耳及第七颅神经的白血病浸润。本文回顾了英文文献中描述的类似病例并讨论了治疗方法。对于已知的无耳部或乳突过程叠加感染症状的白血病患者,化疗或化疗联合放疗是首选治疗方法。手术治疗仅限于需要获取组织进行组织学诊断或需要引流急性感染的病例。