Javaherforooshzadeh Fatemeh, Torfi Yusef
Ahvaz Anesthesiology and Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Anesth Pain Med. 2021 Aug 28;11(4):e117808. doi: 10.5812/aapm.117808. eCollection 2021 Aug.
Klinefelter syndrome (KS) is a genetic disorder that affects men. An augmented incidence of the thromboembolic event described in patients with KS.
A 34-year-old male identified with a definitive diagnosis of KS was hospitalized to our cardiac surgery center through the emergency with chief complaints of acute chest pain and dyspnea. Saddle pulmonary thromboembolism was established from chest Computed Tomography Angiography (CTA). The patient's symptoms resolved after embolectomy via surgery.
There is a tendency for hypercoagulability in KS. This tendency is because of hormonal discrepancy and hereditary thrombophilic factors. So, patients with KS and past medical history of venous thromboembolism necessitate constant oral anticoagulation therapy.
克兰费尔特综合征(KS)是一种影响男性的遗传性疾病。KS患者发生血栓栓塞事件的发生率有所增加。
一名34岁男性被确诊为KS,因急性胸痛和呼吸困难为主诉通过急诊入住我们的心脏外科中心。胸部计算机断层扫描血管造影(CTA)确诊为马鞍形肺血栓栓塞。患者经手术取栓后症状缓解。
KS患者有高凝倾向。这种倾向是由于激素差异和遗传性血栓形成倾向因素。因此,有KS且有静脉血栓栓塞病史的患者需要持续口服抗凝治疗。