Lagha Elyes, Tlili Rami, Azaiez Fares, Romdhane Rym Ben, Bachraoui Kawther, Nouira Nourelhouda, Chaabouni Meriam, Ameur Youssef Ben
Cardiology Department of Mongi Slim University Hospital, La Marsa, Tunis, Tunisia.
Emergency Department of Mongi Slim University Hospital, La Marsa, Tunis, Tunisia.
Pan Afr Med J. 2020 Sep 18;37(Suppl 1):13. doi: 10.11604/pamj.supp.2020.37.13.25894. eCollection 2020.
Klinefelter syndrome is the most common congenital abnormality causing primary hypogonadism and predisposing to a state of hypercoagulability. We report the case of a 37-year-old man, of Algerian nationality, diagnosed with Klinefelter syndrome admitted to the hospital via the emergency room for acute chest pain and dyspnea. The patient arrived in Tunisia 36 hours ago. On admission, body temperature was 38.2°C, blood pressure, pulse and respiratory rate were 130/70 mmHg, 120/minute and 26/minute, respectively. He had an oxygen saturation of 87% in room air. His electrocardiography revealed a complete right bundle-branch block, chest X-Ray was normal. In front of the clinical presentation and the origin of the patient coming from an endemic country, COVID-19 infection was suspected but ruled out by pharyngeal swabs testing negative by real-time reverse-transcription polymerase chain reaction test and massive pulmonary embolism was diagnosed from his chest computed tomography images. The symptoms improved with anticoagulation treatment.
克兰费尔特综合征是导致原发性性腺功能减退并易引发高凝状态的最常见先天性异常疾病。我们报告一例37岁的阿尔及利亚籍男性病例，该患者因急性胸痛和呼吸困难通过急诊室入院，被诊断为克兰费尔特综合征。患者于36小时前抵达突尼斯。入院时，体温为38.2°C，血压、脉搏和呼吸频率分别为130/70 mmHg、120次/分钟和26次/分钟。其在室内空气中的血氧饱和度为87%。他的心电图显示完全性右束支传导阻滞，胸部X光检查正常。鉴于临床表现以及患者来自流行国家的背景，怀疑其感染了新冠病毒，但实时逆转录聚合酶链反应检测的咽拭子检测结果为阴性，排除了新冠病毒感染，通过胸部计算机断层扫描图像诊断为大面积肺栓塞。经抗凝治疗后症状有所改善。
