Shariatzadeh Hooman, Amiri Shayan, Joudi Samad, Bahrabadi Mehrdad
Department of Orthopaedic Surgery, Iran University of Medical Sciences, Tehran, Iran.
Department of Orthopaedic Surgery, Rasoul-E-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Arch Bone Jt Surg. 2021 Sep;9(5):601-604. doi: 10.22038/abjs.2021.53165.2638.
Schwannomas are the most common nerve sheath tumors which are usually solitary enucleated lesions. Multiple schwannomas are a rare circumstance which may occur with or without other manifestations of neurofibromatosis. In this study, we report the case of a 45-year-old man presenting with pain and swelling in the thigh and popliteal space without any manifestation of neurofibromatosis or neurologic problems. Surgery was performed and revealed four separated tumors in the sciatic nerve which was characteristic of schwannoma and confirmed by pathologic findings. Although multiple schwannomas are frequently associated with neurofibromatosis, the current case demonstrated a patient with multiple schwannomas without any manifestation of neurofibromatosis.
施万细胞瘤是最常见的神经鞘瘤，通常为孤立的有包膜病变。多发性施万细胞瘤是一种罕见情况，可伴有或不伴有神经纤维瘤病的其他表现。在本研究中，我们报告了一例45岁男性病例，该患者大腿和腘窝处出现疼痛和肿胀，无神经纤维瘤病或神经系统问题的任何表现。进行了手术，发现坐骨神经中有四个分离的肿瘤，这是施万细胞瘤的特征，并经病理检查证实。虽然多发性施万细胞瘤常与神经纤维瘤病相关，但本例患者有多发性施万细胞瘤，却无神经纤维瘤病的任何表现。
