Centre for Research and Development, Uppsala University, Region Gävleborg, 801 88 Gävle, Sweden.
Department of Imaging and functional medicine, Division diagnostics, Gävle hospital, Region Gävleborg, 801 88, Gävle, Sweden.
Radiat Prot Dosimetry. 2021 Nov 12;196(3-4):234-240. doi: 10.1093/rpd/ncab154.
The purpose of the present work was to evaluate performance in pulmonary nodule detection, reading times and patient doses for ultra-low dose computed tomography (ULD-CT), standard dose chest CT (SD-CT), and digital radiography (DR). Pulmonary nodules were simulated in an anthropomorphic lung phantom. Thirty cases, 18 with lesions (45 total lesions of 3-12 mm) and 12 without lesions were acquired for each imaging modality. Three radiologists interpreted the cases in a free-response study. Performance was assessed using the JAFROC figure-of-merit (FOM). Performance was not significantly different between ULD-CT and SD-CT (FOMs: 0.787 vs 0.814; ΔFOM: 0.03), but both CT techniques were superior to DR (FOM: 0.541; ΔFOM: 0.31 and 0.28). Overall, the CT modalities took longer time to interpret than DR. ULD chest CT may serve as an alternative to both SD-CT and conventional radiography, considerably reducing dose in the first case and improving diagnostic accuracy in the second.
本研究旨在评估肺结节检测、阅读时间和患者剂量方面的性能，比较超小剂量 CT（ULD-CT）、标准剂量 CT（SD-CT）和数字 X 射线摄影（DR）。在人体肺模型中模拟肺结节。对于每种成像方式，均采集 30 例病例，其中 18 例有病变（45 个 3-12mm 的病变），12 例无病变。3 位放射科医生在自由响应研究中解释了这些病例。使用 JAFROC 性能指标（FOM）评估性能。ULD-CT 和 SD-CT 的性能没有显著差异（FOM：0.787 与 0.814；ΔFOM：0.03），但这两种 CT 技术均优于 DR（FOM：0.541；ΔFOM：0.31 和 0.28）。总的来说，CT 方式的解释时间长于 DR。ULD-CT 可能是 SD-CT 和常规 X 射线摄影的替代方法，在第一种情况下大大降低剂量，在第二种情况下提高诊断准确性。
