Amity Institute of Biotechnology, Amity University, Kolkata, West Bengal, India.
IET Nanobiotechnol. 2021 Feb;15(1):19-27. doi: 10.1049/nbt2.12018. Epub 2021 Feb 2.
Nanomicelles are self-assembling nanosized (usually with particle size within a range of 10 to 100 nm) colloidal dispersions with a hydrophobic core and hydrophilic shell. Owing to its size, solubility, customised surface or its exposure to the environment, nanomicelles show some unique or novel characteristics, which makes it multifunctional and thus makes its use indispensable in biomedical application and various other fields. This review presents the unique properties of nanomicelles that makes it different from other particles and paves its way to be used as drug delivery agent and many other biological uses or applications. It also emphasises on the drug encapsulation ability of the nanomicelles and different technique of drug loading and delivery along with its advantages and disadvantages.
纳米胶束是自组装的纳米级胶体分散体(通常粒径在 10 至 100nm 范围内),具有疏水核和亲水壳。由于其尺寸、溶解度、定制表面或对环境的暴露,纳米胶束表现出一些独特或新颖的特性,使其具有多功能性,因此在生物医学应用和其他各种领域中都不可或缺。本综述介绍了纳米胶束的独特性质,使其有别于其他颗粒,并为其作为药物传递剂和许多其他生物用途或应用铺平了道路。它还强调了纳米胶束的药物包封能力,以及不同的药物加载和递送技术及其优缺点。