Koyama Shunsuke, Takahashi Fumiya, Saito Hayate, Yorimitsu Hideki
Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Org Lett. 2021 Nov 5;23(21):8590-8594. doi: 10.1021/acs.orglett.1c03316. Epub 2021 Oct 25.
Treatment of propargylic ethers with sodium dispersion in the presence of lithium iodide results in the generation of the corresponding carbanion species via cleavage of the propargylic C-O bond. The anionic species react with trimethoxyborane to yield the allenylboronates including highly substituted ones that are difficult to synthesize.
在碘化锂存在下，用钠分散体处理炔丙基醚，通过炔丙基碳 - 氧键的断裂生成相应的碳负离子物种。这些阴离子物种与三甲氧基硼烷反应，生成烯丙基硼酸酯，包括难以合成的高度取代的烯丙基硼酸酯。
