Centre for Viral Zoonoses, Department Medical Virology, University of Pretoria, Pretoria 0001, South Africa.
HIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban 4001, South Africa.
Viruses. 2021 Oct 1;13(10):1978. doi: 10.3390/v13101978.
-borne viruses such as bluetongue, African horse sickness, and Schmallenberg virus cause major economic burdens due to animal outbreaks in Africa and their emergence in Europe and Asia. However, little is known about the role of as vectors for zoonotic arboviruses. In this study, we identify both veterinary and zoonotic arboviruses in pools of biting midges in South Africa, during 2012-2017. Midges were collected at six surveillance sites in three provinces and screened for , , , and genera; equine encephalosis virus (EEV); and by reverse transcription polymerase chain reaction. In total, 66/331 (minimum infection rate (MIR) = 0.4) pools tested positive for one or more arbovirus. Orthobunyaviruses, including Shuni virus (MIR = 0.1) and EEV (MIR = 0.2) were more readily detected, while only 2/66 (MIR = 0.1) Middelburg virus and 4/66 unknown viruses (MIR = 0.0) were detected. This study suggests as potential vectors of both veterinary and zoonotic arboviruses detected in disease outbreaks in Africa, which may contribute to the emergence of these viruses to new regions.
虫媒病毒，如蓝舌病病毒、非洲马瘟病毒和 Schmallenberg 病毒，由于在非洲暴发动物疫情以及在欧洲和亚洲出现，给动物健康带来了重大经济负担。然而，目前人们对 作为人畜共患虫媒病毒的载体的作用知之甚少。在这项研究中，我们在 2012 年至 2017 年期间，对南非的吸血蠓进行了病毒检测，确定了兽医和人畜共患虫媒病毒。在三个省的六个监测点收集蠓，并通过反转录聚合酶链反应对 、 、 、 和 属；马脑炎病毒（EEV）；和 进行筛查。总共 66/331 个（最小感染率（MIR）=0.4）的病毒池检测出一种或多种虫媒病毒呈阳性。检测到的正粘病毒科病毒包括 Shuni 病毒（MIR=0.1）和 EEV（MIR=0.2），更容易被检测到，而只有 2/66（MIR=0.1）的 Middelburg 病毒和 4/66 种未知的 病毒（MIR=0.0）被检测到。本研究表明，在非洲疾病暴发中检测到的 可能是兽医和人畜共患虫媒病毒的潜在载体，这可能导致这些病毒传播到新的地区。
