Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, 54 Xianlie Road, Guangzhou, 510060, China.
BMC Ophthalmol. 2021 Oct 25;21(1):381. doi: 10.1186/s12886-021-02130-y.
The goals of this work were to report the demographic characteristics of patients with clinically diagnosed endophthalmitis with or without intraocular foreign bodies (IOFBs) and to analyze the causative microorganisms.
A retrospective analysis was conducted on 1257 patients with clinically diagnosed posttraumatic endophthalmitis who were admitted to Zhongshan Ophthalmic Center between January 1, 2013, and August 31, 2020.
Of the 1257 patients with clinically diagnosed posttraumatic endophthalmitis, 452 (36.0%) patients had IOFBs. Male dominance was more common among the patients with IOFBs than the patients without IOFBs. The average age of the patients with IOFBs was older than that of the patients without IOFBs. The most common microbial pathogens in these two groups were Gram-positive cocci and Gram-negative bacilli. Gram-positive bacilli were more common in the patients with IOFBs than in those without IOFBs (17.9 vs. 9.4%), and Bacillus spp. accounted for 12.6 and 5.5%, respectively. Fungi were less abundant in the patients with IOFBs than in those without IOFBs (8.0 vs. 15.6%).
Patients with IOFBs were mostly male and older than those without IOFBs. Gram-positive bacilli were more common and fungi were less common in patients with IOFBs than in those without IOFBs.
本研究旨在报告临床诊断为眼内异物（IOFB）相关和不相关外伤性眼内炎患者的人口统计学特征，并分析其致病微生物。
对 2013 年 1 月 1 日至 2020 年 8 月 31 日期间在中山大学中山眼科中心就诊的 1257 例临床诊断为外伤性眼内炎患者进行回顾性分析。
在 1257 例临床诊断为外伤性眼内炎的患者中，452 例（36.0%）患者有 IOFB。与无 IOFB 的患者相比，有 IOFB 的患者中男性居多。有 IOFB 的患者平均年龄大于无 IOFB 的患者。这两组患者中最常见的微生物病原体均为革兰阳性球菌和革兰阴性杆菌。与无 IOFB 的患者相比，有 IOFB 的患者中革兰阳性杆菌更为常见（17.9%比 9.4%），其中芽孢杆菌属分别占 12.6%和 5.5%。有 IOFB 的患者中真菌较少（8.0%比 15.6%）。
有 IOFB 的患者以男性和老年人为主。与无 IOFB 的患者相比，有 IOFB 的患者中革兰阳性杆菌更为常见，真菌较少。
