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中国山西省基于人群的慢性阻塞性肺疾病患病率及危险因素调查。

A population-based survey of the prevalence and risk factors of chronic obstructive pulmonary disease in Shanxi Province, China.

机构信息

Department of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital Shanxi Academy of Medical Sciences, Taiyuan, Shanxi Province, China.

Department of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital Shanxi Academy of Medical Sciences, Taiyuan, Shanxi Province, China.

出版信息

Rev Clin Esp (Barc). 2022 Apr;222(4):218-228. doi: 10.1016/j.rceng.2021.04.011. Epub 2021 Oct 23.

Abstract

BACKGROUND

Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease which can cause organ damage and even death. For the first time, the prevalence and risk factors of COPD in Shanxi Province (China) were evaluated in this study.

METHODS

A population-based survey was conducted in 2015 based on the Shanxi Province population (age ≥ 20). COPD was diagnosed according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) standard (2017).

RESULTS

A total of 5636 participants with reliable post-bronchodilator results were selected. The prevalence of spirometry-defined COPD among the population (age ≥ 20) was 6.4% (95% CI 5.8-7.1) and was more prevalent in men (9.7%, 95% CI 8.6-10.9) than women (3.9%, 95% CI 3.2-4.6). The multivariate-adjusted analysis demonstrated that sex, age, education, smoking, chronic cough during childhood (age ≤ 14), and a family history of parents with respiratory diseases were related to the prevalence of COPD risk. On the contrary, among rural residents living with smokers, a history of pneumonia or bronchitis during childhood, BMI, use of biomass energy, prolonged exposure to particulate matter 2.5, and a family history of parents with respiratory diseases did not show a significant correlation to COPD.

CONCLUSIONS

We have identified a high prevalence of COPD and its determinants in Shanxi province. The prevention of COPD and its early detection is a health priority in this province.

摘要

背景

慢性阻塞性肺疾病(COPD)是一种常见的慢性呼吸道疾病,可导致器官损伤甚至死亡。本研究首次评估了山西省(中国)COPD 的患病率和危险因素。

方法

2015 年,基于山西省人口(年龄≥20 岁)进行了一项基于人群的调查。根据全球慢性阻塞性肺疾病倡议(GOLD)标准(2017 年)诊断 COPD。

结果

共纳入 5636 名有可靠支气管扩张后结果的参与者。人群中(年龄≥20 岁)肺量计定义的 COPD 患病率为 6.4%(95%CI 5.8-7.1),男性(9.7%,95%CI 8.6-10.9)患病率高于女性(3.9%,95%CI 3.2-4.6)。多变量调整分析表明,性别、年龄、教育程度、吸烟、儿童期慢性咳嗽(年龄≤14 岁)和父母有呼吸道疾病史与 COPD 风险的患病率相关。相反,在与吸烟者一起居住的农村居民中,儿童期肺炎或支气管炎史、BMI、使用生物质能源、长时间接触 2.5 微米颗粒物以及父母有呼吸道疾病史与 COPD 无显著相关性。

结论

我们已经确定了山西省 COPD 及其决定因素的高患病率。预防 COPD 及其早期发现是该省的健康重点。

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