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动态心电图检测联合小剂量倍他乐克在肝癌切除术后心律失常患者诊断与治疗中的应用。

Dynamic Electrocardiogram under P Wave Detection Algorithm Combined with Low-Dose Betaloc in Diagnosis and Treatment of Patients with Arrhythmia after Hepatocarcinoma Resection.

机构信息

Department of Cardiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang, China.

Department of Surgery, Ningbo Yinzhou No. 2 Hospital, Ningbo 315199, Zhejiang, China.

出版信息

J Healthc Eng. 2021 Oct 16;2021:6034180. doi: 10.1155/2021/6034180. eCollection 2021.

Abstract

This work aimed to study the diagnostic value of dynamic electrocardiogram (ECG) based on P wave detection algorithm for arrhythmia after hepatectomy in patients with primary liver cancer, and to compare the therapeutic effect of different doses of Betaloc. P wave detection algorithm was introduced for ECG automatic detection and analysis, which can be used for early diagnosis of arrhythmia. Sixty patients with arrhythmia after hepatectomy for primary liver cancer were selected as the research objects. They were randomly divided into control group, SD group, MD group, and HD group, with 15 cases in each group. No Betaloc, low-dose (≤47.5 mg), medium-dose (47.5-95 mg), and high-dose (142.5-190 mg) Betaloc were used for treatment. As a result, P wave detection algorithms can mark P waves that may be submerged in strong interference. P waves from arrhythmia database were used to verify the performance of the proposed algorithm. The prediction precision (Pp) of ventricular arrhythmia and atrial arrhythmia was 98.53% and 98.76%, respectively. Systolic blood pressure (117.35 ± 7.33, 126.44 ± 9.38, and 116.02 ± 8.2) mmHg in SD group, MD group, and HD group was significantly lower than that in control group (140.3 ± 7.21) mmHg after two weeks of treatment. Moreover, those of SD group and HD group were significantly lower than MD group ( < 0.05). The effective rate of cardiac function improvement in SD group (72.35 ± 1.21%) was significantly higher than that in control group, MD group, and HD group (38.2 ± 0.98%, 65.12 ± 1.33%, and 60.43 ± 1.25%; < 0.05). In short, dynamic ECG based on P wave detection algorithm had high diagnostic value for arrhythmia after hepatectomy in patients with primary liver cancer. It was safe and effective for patients to choose small dose of Betaloc.

摘要

本研究旨在探讨基于 P 波检测算法的动态心电图对原发性肝癌肝切除术后心律失常的诊断价值,并比较不同剂量倍他乐克的治疗效果。P 波检测算法被引入心电图自动检测和分析中,可用于心律失常的早期诊断。选取 60 例原发性肝癌肝切除术后心律失常患者作为研究对象,随机分为对照组、SD 组、MD 组和 HD 组,每组 15 例。分别给予对照组、低剂量(≤47.5mg)、中剂量(47.5-95mg)和高剂量(142.5-190mg)倍他乐克治疗。结果表明,P 波检测算法能够标记可能被强干扰淹没的 P 波。使用心律失常数据库中的 P 波对所提出算法的性能进行验证,室性心律失常和房性心律失常的预测精度(Pp)分别为 98.53%和 98.76%。治疗 2 周后,SD 组、MD 组和 HD 组的收缩压(117.35±7.33、126.44±9.38 和 116.02±8.2mmHg)明显低于对照组(140.3±7.21mmHg),且 SD 组和 HD 组明显低于 MD 组(<0.05)。SD 组心功能改善有效率(72.35±1.21%)明显高于对照组、MD 组和 HD 组(38.2±0.98%、65.12±1.33%和 60.43±1.25%;<0.05)。总之,基于 P 波检测算法的动态心电图对原发性肝癌肝切除术后心律失常具有较高的诊断价值,小剂量倍他乐克治疗安全有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fb/8541856/895d7981e83c/JHE2021-6034180.001.jpg

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