Department of Medical Statistics, School of Public Health, Sun Yat-Sen University, Guangzhou, China.
Sun Yat‑Sen Global Health Institute, Institute of State Governance, Sun Yat-Sen University, Guangzhou, China.
JMIR Mhealth Uhealth. 2023 May 8;11:e44513. doi: 10.2196/44513.
Requesting and disclosing HIV serostatus is associated with a reduction in HIV transmission among men who have sex with men (MSM). However, the reliability of common methods for HIV serostatus request and disclosure is inadequate. Validated approaches for requesting and disclosing HIV serostatus are necessary.
The objective of this study was to investigate the use of the HIV e-report as authentic evidence of HIV serostatus among the MSM community in Guangzhou, China. Additionally, the study aimed to explore its correlation with HIV serostatus requesting and disclosure receiving behavior.
This study is a subgroup analysis of a cluster randomized controlled trial (RCT) that enrolled 357 participants during the first year. Participants in this RCT were recruited from the WeChat-based HIV testing service miniprogram developed by Guangzhou Center for Disease Control and Prevention, China. Participants completed web-based questionnaires at baseline and at the month 3 follow-up, which covered sociodemographic characteristics, HIV-related information, HIV serostatus requests, receiving HIV serostatus disclosures, and HIV e-report usage. Univariate and multivariate logistic regressions were used for data analysis.
The WeChat-based HIV e-report was available in Guangzhou when the RCT project started. At the month 3 follow-up, 32.2% (115/357) of participants had their own HIV e-reports, and 37.8% (135/357) of them had received others' HIV e-reports. In all, 13.1% (27/205) and 10.5% (16/153) of participants started to use HIV e-reports to request the HIV serostatus from regular and casual male sex partners, respectively. Moreover, 27.3% (42/154) and 16.5% (18/109) of the regular and casual male sex partners, respectively, chose HIV e-reports to disclose their HIV serostatus. Compared to MSM who did not have HIV e-reports, those who had HIV e-reports and stated, "I had had my own HIV e-report(s) but hadn't sent to others" (multivariate odds ratio 2.71, 95% CI 1.19-6.86; P=.02) and "I had had my own HIV e-reports and had sent to others" (multivariate odds ratio 2.67, 95% CI 1.07-7.73; P=.048) were more likely to request HIV serostatus from their partners. However, no factor was associated with receiving an HIV serostatus disclosure from partners.
The HIV e-report has been accepted by the MSM community in Guangzhou and could be applied as a new optional approach for HIV serostatus requests and disclosures. This innovative intervention could be effective in promoting infectious disease serostatus disclosure among the related high-risk population.
ClinicalTrials.gov NCT03984136; https://clinicaltrials.gov/show/NCT03984136.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1186/s12879-021-06484-y.
请求和披露 HIV 血清阳性状态与男男性行为者（MSM）中 HIV 传播的减少有关。然而，常见的 HIV 血清状态请求和披露方法的可靠性不足。需要验证的方法来请求和披露 HIV 血清阳性状态。
本研究旨在调查在中国广州的 MSM 社区中，HIV 电子报告作为 HIV 血清阳性状态的真实证据的使用情况。此外，本研究旨在探讨其与 HIV 血清状态请求和披露接收行为的相关性。
本研究是一项群组随机对照试验（RCT）的子组分析，该试验在第一年招募了 357 名参与者。该 RCT 的参与者是从中国广州疾病预防控制中心开发的基于微信的 HIV 检测服务小程序中招募的。参与者在基线和第 3 个月随访时完成了基于网络的问卷，涵盖了社会人口统计学特征、HIV 相关信息、HIV 血清状态请求、接受 HIV 血清状态披露以及 HIV 电子报告使用情况。使用单变量和多变量逻辑回归进行数据分析。
当 RCT 项目开始时，广州已经可以使用基于微信的 HIV 电子报告。在第 3 个月随访时，32.2%（115/357）的参与者拥有自己的 HIV 电子报告，37.8%（135/357）的参与者收到了其他人的 HIV 电子报告。共有 13.1%（27/205）和 10.5%（16/153）的参与者开始分别向固定和偶然的男男性行为伴侣使用 HIV 电子报告请求 HIV 血清阳性状态。此外，27.3%（42/154）和 16.5%（18/109）的固定和偶然的男男性行为伴侣分别选择使用 HIV 电子报告来披露他们的 HIV 血清阳性状态。与没有 HIV 电子报告的 MSM 相比，那些拥有 HIV 电子报告并表示“我已经有了自己的 HIV 电子报告，但尚未发送给他人”（多变量优势比 2.71，95%置信区间 1.19-6.86；P=.02）和“我已经有了自己的 HIV 电子报告并已发送给他人”（多变量优势比 2.67，95%置信区间 1.07-7.73；P=.048）更有可能向伴侣请求 HIV 血清阳性状态。然而，没有任何因素与从伴侣处收到 HIV 血清阳性状态披露有关。
HIV 电子报告已被广州的 MSM 社区接受，可作为 HIV 血清阳性状态请求和披露的新可选方法。这种创新干预措施可能有助于促进相关高危人群传染病血清阳性状态的披露。
ClinicalTrials.gov NCT03984136；https://clinicaltrials.gov/show/NCT03984136。
国际注册报告标识符（IRRID）：RR2-10.1186/s12879-021-06484-y。
