Clinical Laboratory Center, Jiangsu Taizhou People's Hospital, Taizhou, Jiangsu, P. R. China.
J Int Med Res. 2021 Oct;49(10):3000605211047277. doi: 10.1177/03000605211047277.
is an anaerobic bacterium with a reportedly high isolation rate; however, it rarely causes bloodstream infections. Patients with hypertension are at increased risk of developing anaerobic bacterial infection. In this study, we report a case of bacteremia caused by in a patient with renal hypertension and gastrointestinal hemorrhage. This study describes the clinical manifestations of bloodstream infection involving to provide guidance for laboratory technicians and clinicians. A 42-year-old Chinese man was admitted for gastrointestinal hemorrhage and subsequently diagnosed with anaerobic blood infection. The pathogenic bacteria isolated from anaerobic blood culture bottles were identified as by using an automatic bacterial identification instrument and mass spectrometry (MS). is an intestinal opportunistic pathogen that can invade the intestinal mucosa and cause anaerobic bloodstream infection. Two or more sets of blood cultures and MS identification can greatly improve the positive detection rate of blood cultures of anaerobic bacteria. Furthermore, the increased drug resistance of anaerobic bacteria necessitates drug sensitivity tests for anaerobic bacteria in many hospitals. Thus, the early prevention and control of primary diseases with appropriate diagnoses and timely anti-infection therapies are necessary to reduce bloodstream infection.
是一种厌氧菌,据报道其分离率较高;然而,它很少引起血流感染。高血压患者发生厌氧菌感染的风险增加。本研究报告了一例由肾性高血压和胃肠道出血患者的 引起的菌血症。本研究描述了涉及 的血流感染的临床表现,为实验室技术人员和临床医生提供指导。一名 42 岁的中国男性因胃肠道出血入院,随后被诊断为厌氧菌血感染。使用自动细菌鉴定仪和质谱(MS)从厌氧血培养瓶中分离出的病原菌鉴定为 。是肠道机会致病菌,可侵犯肠道黏膜,引起厌氧血流感染。两套或两套以上的血培养和 MS 鉴定可大大提高厌氧菌血培养的阳性检出率。此外,厌氧菌的耐药性增加,许多医院都需要进行厌氧菌药敏试验。因此,早期预防和控制原发性疾病,进行适当的诊断,并及时进行抗感染治疗,对于降低 血流感染非常必要。