Division of Medical Sciences. Faculty of Medicine, University of British Columbia, University of Victoria, 713 Johnson street, Victoria, BC, V8W1M8, Canada.
Centre for Gender and Sexual Health Equity, Vancouver, BC, Canada.
AIDS Behav. 2022 May;26(5):1607-1617. doi: 10.1007/s10461-021-03513-4. Epub 2021 Oct 27.
Given sub-optimal HIV care outcomes for people living with HIV (PLWH) post-release from incarceration, we systematically searched peer-reviewed literature (2010-2021) describing controlled trial interventions aimed at improving Antiretroviral Therapy (ART) adherence and care linkage following release from correctional facilities for PLWH. Of 392 studies, 16 (4%) met the inclusion criteria. All studies were conducted in the United States and involved some form of intensive case management. Trials that scored highest in terms of study quality provided cell phones for engagement, reported sustained viral load suppression as a measurable outcome to infer ART adherence, and measured longitudinal data collected for at least 3-to-6 months following release. The two trials that demonstrated improved HIV viral load suppression involved Peer Navigators, and incentivized undetectable viral load, respectively. Facilitating support for addictions and addressing other social and structural barriers to achieving optimal health is also of vital importance in bridging care gaps for PLWH.
鉴于从监禁中释放后的艾滋病毒感染者(PLWH)的艾滋病毒护理结果不理想,我们系统地搜索了同行评议文献(2010-2021 年),描述了旨在改善从矫正设施释放后抗逆转录病毒治疗(ART)依从性和护理衔接的对照试验干预措施。在 392 项研究中,有 16 项(4%)符合纳入标准。所有研究均在美国进行,涉及某种形式的强化病例管理。在研究质量方面得分最高的试验为参与提供了手机,报告了持续的病毒载量抑制作为推断 ART 依从性的可衡量结果,并测量了释放后至少 3 至 6 个月的纵向数据。两项表明 HIV 病毒载量抑制得到改善的试验涉及同伴导航员,分别激励病毒载量不可检测。为了弥合 PLWH 的护理差距,促进对成瘾的支持和解决实现最佳健康的其他社会和结构性障碍也至关重要。