瑜伽对 HIV+ 个体监禁后抗逆转录病毒药物依从性的影响。
Effect of Yoga on Antiretroviral Adherence Postincarceration in HIV+ Individuals.
机构信息
University of Maryland School of Social Work, Baltimore, MD, USA.
Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
出版信息
J Correct Health Care. 2020 Jan;26(1):83-94. doi: 10.1177/1078345819897924. Epub 2020 Feb 24.
The negative impacts of stress on antiretroviral therapy (ART) adherence and the many stressors faced by people returning from incarceration support the need for stress reduction interventions for this population. We hypothesized that 37 returning citizens living with HIV and substance use problems randomized to a 12-session weekly yoga intervention would experience improved ART adherence, lower viral loads, and lower heart rate and blood pressure as compared to 36 people randomized to treatment as usual (TAU). We found that ART adherence increased for yoga participants and decreased for TAU participants. There were no significant changes for viral load, heart rate, or blood pressure. The lack of statistically significant effects may be due to a small sample size and enrollment of people largely in HIV treatment. Studies with larger sample sizes and participants exhibiting low ART adherence are warranted to better understand yoga's impact.
压力对抗逆转录病毒疗法（ART）依从性的负面影响，以及从监禁中返回的人面临的许多压力源，都支持需要为这一人群实施减压干预。我们假设，37 名患有 HIV 且存在药物使用问题的回归公民随机分为每周 12 次瑜伽干预组和常规治疗组（TAU），与 TAU 组相比，瑜伽干预组的 ART 依从性会提高，病毒载量会降低，心率和血压会降低。我们发现瑜伽组的 ART 依从性增加，而 TAU 组的依从性下降。病毒载量、心率或血压没有显著变化。没有统计学意义的效果可能是由于样本量小，以及主要招募的是 HIV 治疗患者。需要更大样本量和 ART 依从性较低的参与者的研究，以更好地了解瑜伽的影响。
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