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球囊导管与单独使用催产素用于有一次剖宫产史且宫颈条件不佳的产妇引产:一项多中心回顾性研究。

Balloon catheter vs oxytocin alone for induction of labor in women with one previous cesarean section and an unfavorable cervix: a multicenter, retrospective study.

机构信息

Department of Gynecology and Obstetrics, Centre Hospitalier Universitaire de Saint-Étienne, 42055, Saint-Étienne, France.

Service Obstétrique, Centre Hospitalo-Universitaire Grenoble Alpes, CS 10217, 38043, Grenoble, France.

出版信息

Arch Gynecol Obstet. 2022 Aug;306(2):379-387. doi: 10.1007/s00404-021-06298-y. Epub 2021 Oct 28.

Abstract

PURPOSE

To compare the rate of vaginal birth between double-balloon catheter and oxytocin alone for induction of labor in women with one previous cesarean section and an unfavorable cervix.

MATERIALS AND METHODS

A retrospective and observational study was conducted from 2013 to 2017, at the Saint-Etienne University Hospital where women received induction with a double-balloon catheter for 12 h and at the Grenoble Alpes University Hospital where women received induction with a low-dose oxytocin infusion. Primary outcome was the rate of vaginal birth.

RESULTS

Out of 1920 women eligible for attempting a vaginal birth after one previous cesarean section, 501 had a labor induction. Among women with an unfavorable cervix, 160 received a double-balloon catheter in Saint Etienne and 152 received oxytocin alone in Grenoble. The vaginal birth rate was higher in the double-balloon catheter group (61% versus 47% in the oxytocin group). An induction of labor with oxytocin alone reduced chances of vaginal birth (aOR 0.38 CI-95% [0.22-0.66]) compared to cervical ripening with double-balloon catheter. The perinatal morbidity was similar in the two groups. There was, however, 3.9% uterine rupture in the oxytocin group versus 0.6% in the double-balloon group (p = 0.11).

CONCLUSION

For induction of labor in women with one previous cesarean section and with unfavorable cervix, cervical ripening with a double-balloon catheter increases the rate of vaginal birth without increased risk of uterine rupture.

摘要

目的

比较单胎剖宫产史且宫颈条件不佳的产妇,使用双球囊导管与缩宫素单独引产的阴道分娩率。

材料和方法

这是一项回顾性观察研究,于 2013 年至 2017 年在圣艾蒂安大学医院和格勒诺布尔阿尔卑斯大学医院进行,前者对产妇使用双球囊导管引产 12 小时,后者对产妇使用小剂量缩宫素点滴引产。主要结局为阴道分娩率。

结果

在 1920 名有尝试单胎剖宫产术后阴道分娩意愿的产妇中,有 501 名接受了引产。在宫颈条件不佳的产妇中,160 名在圣艾蒂安接受了双球囊导管引产,152 名在格勒诺布尔接受了缩宫素单独引产。双球囊导管组的阴道分娩率更高(61% vs 47%,缩宫素组)。与双球囊导管促宫颈成熟相比,单独使用缩宫素引产降低了阴道分娩的机会(aOR 0.38 CI-95% [0.22-0.66])。两组围产期发病率相似,但缩宫素组子宫破裂率为 3.9%,双球囊组为 0.6%(p=0.11)。

结论

对于单胎剖宫产史且宫颈条件不佳的产妇,使用双球囊导管促宫颈成熟可提高阴道分娩率,且不会增加子宫破裂的风险。

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