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[使用球囊导管对有剖宫产史的女性进行引产:值得吗?]

[Induction of labor in women with previous caesarean delivery with balloon catheter: Is it worth it?].

作者信息

Boujenah J, Fleury C, Tigaizin A, Benbara A, Mounsambote L, Murtada R, Fermaut M, Carbillon L

机构信息

Pôle femme et enfant, groupe hospitalier universitaire Paris Seine Saint-Denis, site Jean-Verdier, avenue du 14 Juillet, 93140 Bondy, France; UFR SMBH, université Paris 13, Sorbonne Paris cité, 93000 Bobigny, France.

Pôle femme et enfant, groupe hospitalier universitaire Paris Seine Saint-Denis, site Jean-Verdier, avenue du 14 Juillet, 93140 Bondy, France.

出版信息

Gynecol Obstet Fertil Senol. 2019 Mar;47(3):273-280. doi: 10.1016/j.gofs.2019.01.008. Epub 2019 Feb 10.

Abstract

OBJECTIF

Balloon catheters for labor induction at term after previous cesarean section is an alternative option to iterative cesarean section. The aim of this study was to analyze the maternal and neonatal outcomes of the trial of labor after cesarean (TOLAC) in women with unfavorable cervix and balloon catheter induction, 2 years after introduction of this process.

METHODS

Unicentric observational study of women with term cephalic singleton, unfavorable cervix (simplified Bishop score<5) after TOLAC using double-balloon catheter. Were analyzed the mode of delivery and severe maternal (uterine rupture, post-partum hemorrhage, severe perineal tears) and neonatal (neonatal unit admission, APGAR<7 at 5minutes, pH<7.1) outcomes. Predictive factors for failed TOLAC were analyzed by using multivariate logistic regression.

RESULTS

Between 2016-2017, 455 (75.4%) women had TOLAC, whose 59 (13%) women with balloon catheter. The overall vaginal delivery (VD) was 73.9%. After Balloon catheter, the VD rate was 50.8%, versus 79.1% after spontaneous labor, and 68.2% after alone oxytocin/artificial membrane rupture induction (P<0.05). Previous VD (aOR 0.176 CI-95% [0.048-0.651]) and prior sweeping membrane (aOR 0.161 CI-95% [0.034-0.761]) was protective for cesarean section after TOLAC. Severe maternal and neonatal morbidities were observed in 10 (17%) and 8 (13.6%) cases, respectively.

CONCLUSION

Double-Balloon catheter is an option for unfavorable cervix and term induction after previous cesarean section. However, the TOLAC in women whose unfavorable cervix is not without maternal and neonatal risk, especially due to its failure.

摘要

目的

对于既往有剖宫产史的足月孕妇,使用球囊导管引产是再次剖宫产的一种替代选择。本研究的目的是分析在引入该方法2年后,宫颈条件不佳且使用球囊导管引产的剖宫产术后阴道试产(TOLAC)的母婴结局。

方法

对足月单胎头位、TOLAC后宫颈条件不佳(简化Bishop评分<5)且使用双球囊导管的孕妇进行单中心观察性研究。分析分娩方式以及严重母体并发症(子宫破裂、产后出血、严重会阴裂伤)和新生儿并发症(入住新生儿重症监护病房、5分钟时阿氏评分<7、pH<7.1)。采用多因素logistic回归分析TOLAC失败的预测因素。

结果

2016年至2017年期间,455名(75.4%)孕妇进行了TOLAC,其中59名(13%)孕妇使用了球囊导管。总体阴道分娩率为73.9%。使用球囊导管后,阴道分娩率为50.8%,自然发动分娩后为79.1%,单独使用缩宫素/人工破膜引产术后为68.2%(P<0.05)。既往阴道分娩(调整后比值比0.176,95%置信区间[0.048 - 0.651])和既往人工剥膜(调整后比值比0.161,95%置信区间[0.034 - 0.761])对TOLAC术后剖宫产具有保护作用。分别有10例(17%)和8例(13.6%)出现严重母体和新生儿并发症。

结论

双球囊导管是既往剖宫产术后宫颈条件不佳且足月引产的一种选择。然而,宫颈条件不佳的孕妇进行TOLAC并非没有母婴风险,尤其是因其失败所致。

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