Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Department of Obstetrics and Gynecology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
J Gynecol Oncol. 2021 Nov;32(6):e94. doi: 10.3802/jgo.2021.32.e94.
Since the human papillomavirus (HPV) vaccine guidelines were developed by the Korean Society of Gynecologic Oncology (KSGO) in 2011, 2016, and 2019, several recent studies on the efficacy and safety of HPV vaccines in middle-aged women and men have been reported. Furthermore, there has been an ongoing debate regarding the efficacy of the HPV vaccine in women with prior HPV infection or who have undergone conization for cervical intraepithelial neoplasia (CIN). We searched and reviewed studies on the efficacy and safety of the HPV vaccine in middle-aged women and men and the efficacy of the HPV vaccine in patients infected with HPV and those who underwent conization for CIN. The KSGO updated their guidelines based on the results of the studies included in this review.
自 2011 年、2016 年和 2019 年韩国妇科肿瘤学会 (KSGO) 制定人乳头瘤病毒 (HPV) 疫苗指南以来,已经有几项关于 HPV 疫苗在中年女性和男性中的疗效和安全性的最新研究报告。此外,对于 HPV 疫苗在既往 HPV 感染或因宫颈上皮内瘤变 (CIN) 而行锥切术的女性中的疗效一直存在争议。我们搜索并回顾了 HPV 疫苗在中年女性和男性中的疗效和安全性以及 HPV 疫苗在 HPV 感染患者和 CIN 锥切术后患者中的疗效的研究。KSGO 根据本综述中包含的研究结果更新了他们的指南。