Emerg Infect Dis. 2021 Dec;27(12):3188-3190. doi: 10.3201/eid2712.210652. Epub 2021 Oct 28.
We used the incidence of spike gene target failures identified during PCR testing to provide an early projection of the prevalence of severe acute respiratory syndrome coronavirus 2 variant B.1.1.7 in a university setting in Texas, USA, before sequencing results were available. Findings from a more recent evaluation validated those early projections.
我们利用聚合酶链反应(PCR)检测中发现的棘突基因靶标失败的发生率,在美国德克萨斯州的一所大学环境中,在获得测序结果之前,对严重急性呼吸综合征冠状病毒 2 变异株 B.1.1.7 的流行情况进行了早期预测。最近的一项评估结果证实了这些早期预测。