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无牙颌和缺牙患者口腔中的唾液免疫球蛋白浓度。

Salivary immunoglobulin concentrations in predentate and edentulous mouths.

作者信息

Grönblad E A, Lindholm K

出版信息

Scand J Dent Res. 1987 Feb;95(1):27-31. doi: 10.1111/j.1600-0722.1987.tb01388.x.

DOI:10.1111/j.1600-0722.1987.tb01388.x
PMID:3470895
Abstract

The concentrations of IgA, IgG and IgM in whole saliva of predentate babies, dentate adults, and edentulous old people, and the salivary IgG concentration of dentate old people, were determined using a solid phase radioimmunoassay. A highly significant difference in IgG concentrations was found between toothless and dentate people. The average IgG concentration in the saliva of edentulous old people was 5.2 mg/1, which was about 20% of that of dentate old people. The salivary IgG content of babies was only 1.7 mg/1, which was in concordance with the low postnatal serum IgG values. The salivary IgA level in this age group was also low. The edentulous old people tended to have decreased IgM values, and the predentate babies tended to have increased IgM values compared with the dentate adults.

摘要

采用固相放射免疫分析法测定了无牙婴儿、有牙成年人和无牙老年人全唾液中IgA、IgG和IgM的浓度,以及有牙老年人唾液中IgG的浓度。结果发现,无牙者和有牙者的IgG浓度存在极显著差异。无牙老年人唾液中IgG的平均浓度为5.2毫克/升,约为有牙老年人的20%。婴儿唾液中IgG含量仅为1.7毫克/升,这与出生后血清IgG值较低相一致。该年龄组唾液中IgA水平也较低。与有牙成年人相比,无牙老年人的IgM值往往降低,无牙婴儿的IgM值往往升高。

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