乳酸杆菌计数高的学龄儿童唾液中的溶菌酶活性和L(+) - 乳酸生成

Lysozyme activity and L(+)-lactic acid production in saliva in schoolchildren with high Lactobacillus counts.

作者信息

Twetman S, Dahllöf G, Wikner S

出版信息

Scand J Dent Res. 1987 Apr;95(2):128-31. doi: 10.1111/j.1600-0722.1987.tb01819.x.

DOI:10.1111/j.1600-0722.1987.tb01819.x

Abstract

Out of 374 schoolchildren, aged 13-15 yr, 42 with high counts of salivary lactobacilli (greater than or equal to 10(5] were selected for this study. Lysozyme activity in saliva and L(+)-lactic acid (LA) production after addition of glucose were determined. The mean values of lysozyme activity and LA concentration were 19.4 micrograms/ml and 1.4 mmol/l respectively. The levels of LA produced without addition of glucose were less than 0.2 mmol/l. The results showed a statistically significant (P less than 0.05) negative correlation between lysozyme activity and the levels of LA produced. The findings of this study suggest that lysozyme may be of importance in limiting acid production in saliva.

摘要

在374名13至15岁的学童中，选择了42名唾液乳酸杆菌计数高（大于或等于10⁵）的儿童进行本研究。测定了唾液中的溶菌酶活性以及添加葡萄糖后的L(+)-乳酸（LA）产量。溶菌酶活性和LA浓度的平均值分别为19.4微克/毫升和1.4毫摩尔/升。未添加葡萄糖时产生的LA水平低于0.2毫摩尔/升。结果显示溶菌酶活性与产生的LA水平之间存在统计学上显著的（P<0.05）负相关。本研究结果表明，溶菌酶可能在限制唾液中酸的产生方面具有重要作用。