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FOLFOX-HAIC active in large HCC.

作者信息

Sidaway Peter

机构信息

Nature Reviews Clinical Oncology, .

出版信息

Nat Rev Clin Oncol. 2022 Jan;19(1):5. doi: 10.1038/s41571-021-00577-y.

DOI:10.1038/s41571-021-00577-y
PMID:34711952
Abstract
摘要

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FOLFOX-HAIC active in large HCC.FOLFOX-HAIC对大型肝癌有效。
Nat Rev Clin Oncol. 2022 Jan;19(1):5. doi: 10.1038/s41571-021-00577-y.
2
Hepatic artery infusion chemotherapy using mFOLFOX versus transarterial chemoembolization for massive unresectable hepatocellular carcinoma: a prospective non-randomized study.使用改良FOLFOX方案的肝动脉灌注化疗与经动脉化疗栓塞术治疗巨大不可切除肝细胞癌的前瞻性非随机研究。
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Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: analysis of 48 cases.肝动脉灌注化疗治疗伴有门静脉癌栓的晚期肝细胞癌：48例分析
Cancer. 2002 Aug 1;95(3):588-95. doi: 10.1002/cncr.10694.
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Repetitive short-course hepatic arterial infusion chemotherapy with high-dose 5-fluorouracil and cisplatin in patients with advanced hepatocellular carcinoma.晚期肝细胞癌患者采用高剂量5-氟尿嘧啶和顺铂进行重复短疗程肝动脉灌注化疗。
Cancer. 2007 Jul 1;110(1):129-37. doi: 10.1002/cncr.22759.
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A randomized study of cisplatin and 5-FU hepatic arterial infusion chemotherapy with or without adriamycin for advanced hepatocellular carcinoma.一项关于顺铂和5-氟尿嘧啶肝动脉灌注化疗联合或不联合阿霉素治疗晚期肝细胞癌的随机研究。
Cancer Chemother Pharmacol. 2015 Apr;75(4):739-46. doi: 10.1007/s00280-015-2692-0. Epub 2015 Feb 7.
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Randomized, prospective, comparative study on the effects and safety of sorafenib vs. hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma with portal vein tumor thrombosis.随机、前瞻性、比较研究索拉非尼与肝动脉灌注化疗治疗伴有门静脉癌栓的晚期肝细胞癌的疗效和安全性。
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Comparison of hepatic arterial infusion chemotherapy versus sorafenib monotherapy in patients with advanced hepatocellular carcinoma.肝动脉灌注化疗与索拉非尼单药治疗晚期肝细胞癌患者的比较。
J Dig Dis. 2015 Sep;16(9):505-12. doi: 10.1111/1751-2980.12267.
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FOLFOX-HAIC for Unresectable Large Hepatocellular Carcinoma: The Effectiveness Has Yet to be Determined.
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Current status of hepatocellular carcinoma treatment in Japan: hepatic arterial infusion chemotherapy.日本肝细胞癌治疗的现状：肝动脉灌注化疗。
Clin Drug Investig. 2012 Aug 8;32 Suppl 2:15-23. doi: 10.1007/BF03265493.
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Long-term clinical outcomes of hepatic arterial infusion chemotherapy with cisplatin with or without 5-fluorouracil in locally advanced hepatocellular carcinoma.局部进展期肝细胞癌应用顺铂联合或不联合氟尿嘧啶肝动脉灌注化疗的长期临床疗效。
J Cancer Res Clin Oncol. 2011 Apr;137(4):659-67. doi: 10.1007/s00432-010-0917-5. Epub 2010 Jun 16.

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Efficacy of transarterial chemoembolization-hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis.经动脉化疗栓塞-肝动脉灌注化疗联合靶向治疗与免疫治疗在伴有门静脉癌栓的肝细胞癌中的疗效
Oncol Lett. 2025 May 23;30(1):363. doi: 10.3892/ol.2025.15109. eCollection 2025 Jul.
2
FOLFOX-HAIC combined with PD-1 inhibitor immunotherapy significantly improves survival in patients with advanced hepatocellular carcinoma.FOLFOX-HAIC联合PD-1抑制剂免疫疗法可显著提高晚期肝细胞癌患者的生存率。
Am J Transl Res. 2025 Apr 15;17(4):2577-2590. doi: 10.62347/YMXR8481. eCollection 2025.
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Disease Burden Affects Outcomes in Pediatric and Young Adult B-Cell Lymphoblastic Leukemia After Commercial Tisagenlecleucel: A Pediatric Real-World Chimeric Antigen Receptor Consortium Report.商业用 tisagenlecleucel 治疗儿童和青年 B 细胞淋巴母细胞白血病后的疾病负担对结果的影响：儿科嵌合抗原受体联盟报告。
J Clin Oncol. 2022 Mar 20;40(9):945-955. doi: 10.1200/JCO.20.03585. Epub 2021 Dec 9.
Development of a Nomogram for Prognostic Prediction of Large Hepatocellular Carcinoma With HBV After TACE Combined Conversion Therapy.
TACE联合转化治疗后HBV相关大肝癌预后预测列线图的构建
Hepat Med. 2025 Apr 7;17:1-12. doi: 10.2147/HMER.S481334. eCollection 2025.
4
Hepatic arterial infusion chemotherapy (HAIC) combined with Tislelizumab and Lenvatinib for unresectable hepatocellular carcinoma: a retrospective single-arm study.肝动脉灌注化疗（HAIC）联合替雷利珠单抗和仑伐替尼治疗不可切除肝细胞癌：一项回顾性单臂研究
Cell Oncol (Dordr). 2024 Dec;47(6):2265-2276. doi: 10.1007/s13402-024-01015-8. Epub 2024 Nov 25.
5
The AFCRPLITY score for predicting the prognosis of immunotherapy combined with local-regional therapy in unresectable hepatocellular carcinoma.预测不可切除肝细胞癌免疫治疗联合局部区域治疗预后的AFCRPLITY评分。
Ther Adv Med Oncol. 2024 Nov 19;16:17588359241297080. doi: 10.1177/17588359241297080. eCollection 2024.
6
Camrelizumab, apatinib and hepatic artery infusion chemotherapy combined with microwave ablation for advanced hepatocellular carcinoma.卡瑞利珠单抗、阿帕替尼及肝动脉灌注化疗联合微波消融治疗晚期肝细胞癌
World J Gastrointest Oncol. 2024 Aug 15;16(8):3481-3495. doi: 10.4251/wjgo.v16.i8.3481.
7
Efficacy and safety of HAIC combined with tyrosine kinase inhibitors HAIC monotherapy for advanced hepatocellular carcinoma: a multicenter propensity score matching analysis.肝动脉灌注化疗联合酪氨酸激酶抑制剂与肝动脉灌注化疗单药治疗晚期肝细胞癌的疗效和安全性：一项多中心倾向评分匹配分析
Front Pharmacol. 2024 Jul 31;15:1410767. doi: 10.3389/fphar.2024.1410767. eCollection 2024.
8
Association of serum AFP trajectories and hepatocellular carcinoma outcomes after hepatic arterial infusion chemotherapy: A longitudinal, multicenter study.血清 AFP 轨迹与肝动脉灌注化疗后肝细胞癌结局的关系：一项纵向、多中心研究。
Cancer Med. 2024 Jun;13(11):e7319. doi: 10.1002/cam4.7319.
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Atezolizumab Plus Bevacizumab Combined with Transarterial Embolization Plus Hepatic Arterial Infusion Chemotherapy for Unresectable Hepatocellular Carcinoma with a Diameter >8 Cm: A Retrospective Study.阿替利珠单抗联合贝伐单抗联合经动脉栓塞加肝动脉灌注化疗治疗直径>8厘米的不可切除肝细胞癌：一项回顾性研究
J Hepatocell Carcinoma. 2024 Feb 26;11:399-409. doi: 10.2147/JHC.S439001. eCollection 2024.
10
Hepatic Artery Infusion Chemotherapy Sequential Hepatic Artery Embolization Combined with Operation in the Treatment of Recurrent Massive Hepatocellular Carcinoma Achieved Pathological Complete Response: A Case Report.肝动脉灌注化疗序贯肝动脉栓塞联合手术治疗复发性巨块型肝细胞癌获病理完全缓解：1例报告
Pharmgenomics Pers Med. 2023 Nov 1;16:949-958. doi: 10.2147/PGPM.S426791. eCollection 2023.