双氟尼酸引起的中性粒细胞减少症。

Diflunisal-induced neutropenia.

作者信息

McLean C A, Begley C G, Harris R A

出版信息

Aust N Z J Med. 1986 Dec;16(6):811-2. doi: 10.1111/j.1445-5994.1986.tb00046.x.

DOI:10.1111/j.1445-5994.1986.tb00046.x

Abstract

We report a case of neutropenia associated with the use of diflunisal. The neutropenia occurred with initial administration and on subsequent inadvertent rechallenge with the drug. Bone marrow biopsy showed active granulopoiesis and an immune-mediated mechanism for this response is postulated.

摘要

我们报告一例与双氟尼酸使用相关的中性粒细胞减少症。中性粒细胞减少症在首次用药时以及随后意外再次用药时均有发生。骨髓活检显示有活跃的粒细胞生成，并推测这种反应存在免疫介导机制。