类风湿关节炎患者使用左旋咪唑治疗期间出现的中性粒细胞减少症。
Neutropenia during treatment of rheumatoid arthritis with levamisole.
作者信息
Williams G T, Johnson S A, Dieppe P A, Huskisson E C
出版信息
Ann Rheum Dis. 1978 Aug;37(4):366-9. doi: 10.1136/ard.37.4.366.
Abstract
Of 60 patients with rheumatoid arthritis treated with levamisole 35% showed a persistent decrease in neutrophil counts from pre-treatment levels and 6 (10%) develped severe neutropenia of less than 1.0 X 10(9)/1. One of these neutropenic patients recoverd without stopping therapy and the other 5 patients recovered rapidly when the drug was withdrawn. In some patients neutropenia recurred on reinstitution of levamisole.
摘要
在60例接受左旋咪唑治疗的类风湿性关节炎患者中，35%的患者中性粒细胞计数持续低于治疗前水平，6例（10%）出现严重中性粒细胞减少，低于1.0×10⁹/L。其中1例中性粒细胞减少患者未停药即康复，另外5例患者停药后迅速康复。部分患者重新使用左旋咪唑后中性粒细胞减少复发。
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DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association.类风湿关节炎的诊断标准：美国风湿病协会委员会1958年修订版。
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Graphic representation of pain.疼痛的图形表示。
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[Letter: Agranulocytosis during treatment with levamisole].[信件：左旋咪唑治疗期间的粒细胞缺乏症]
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Br J Haematol. 1975 Sep;31(1):103-10. doi: 10.1111/j.1365-2141.1975.tb00837.x.
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