Haas Johannes-Peter, Weimann Vincent, Feist Eugen
Deutsches Zentrum für Kinder- und Jugendrheumatologie, Zentrum für Schmerztherapie junger Menschen, Kinderklinik Garmisch-Partenkirchen gGmbH, Gehfeldstr. 24, 82467, Garmisch-Partenkirchen, Deutschland.
Rheumatologie, Helios Fachklinik Vogelsang-Gommern, Vogelsang-Gommern, Deutschland.
Z Rheumatol. 2022 Feb;81(1):4-13. doi: 10.1007/s00393-021-01114-z. Epub 2021 Oct 28.
The spectrum of polyarthritic diseases in childhood as well as in adulthood is wide. In the differential diagnostics different age-related diseases must be taken into consideration. Although, a clear similarity is obvious in all age groups for the classical diseases of polyarticular juvenile idiopathic arthritis and rheumatoid arthritis with respect to the pathogenesis, clinical manifestation and treatment options, this review points to specific differences. The prognosis of polyarthritis in children mainly depends on the joint manifestation, whereas extra-articular comorbidities play a predominant role in the older adult population.
儿童和成人的多关节疾病谱都很广泛。在鉴别诊断中,必须考虑不同的与年龄相关的疾病。尽管在所有年龄组中,多关节型幼年特发性关节炎和类风湿关节炎这两种经典疾病在发病机制、临床表现和治疗选择方面存在明显的相似性,但本综述指出了它们的具体差异。儿童多关节炎的预后主要取决于关节表现,而关节外合并症在老年人群中起主要作用。