Department of Paediatric Neurosurgery, Queen's Medical Centre, Derby Road, Nottingham, NG7 2UH, UK.
Department of Clinical Microbiology, Queen's Medical Centre, Nottingham, UK.
Childs Nerv Syst. 2022 Jul;38(7):1385-1388. doi: 10.1007/s00381-021-05401-7. Epub 2021 Oct 28.
Psychrobacter piechaudii is a recently described species of Gram-negative bacteria in the Moraxellaceae family. No cases of human infection due to this species have been described before. We report the case of an ex-premature infant girl with hydrocephalus secondary to intraventricular haemorrhage who underwent multiple cerebrospinal fluid (CSF) shunt operations. She ultimately developed Psychrobacter piechaudii meningitis, presenting as ventriculoperitoneal shunt dysfunction and wound leak, which necessitated removal of the shunt, a period of external ventricular drainage and antibiotics. We found this organism to be sensitive to intravenous ceftazidime (50 mg/kg) and ciprofloxacin, and a 7-10 day treatment course prior to shunt re-insertion (and 3 week total course) was sufficient. The patient is well post-operatively. To the best of our knowledge, this is the first reported case of Psychrobacter piechaudii infection in a human.
皮氏食酸菌是莫拉氏菌科中最近描述的一种革兰氏阴性细菌。以前没有报道过该物种引起人类感染的病例。我们报告了一例患有脑积水的早产儿女孩，该脑积水继发于脑室出血，她接受了多次脑脊髓液（CSF）分流手术。她最终发展为皮氏食酸菌脑膜炎，表现为脑室腹腔分流功能障碍和伤口漏，需要移除分流管、进行外部脑室引流和使用抗生素。我们发现该生物体对静脉注射头孢他啶（50mg/kg）和环丙沙星敏感，在重新插入分流管之前进行 7-10 天的治疗（总疗程 3 周）就足够了。患者术后恢复良好。据我们所知，这是首例人类感染皮氏食酸菌的报告病例。
