针灸联合中药治疗 2 型糖尿病的疗效和安全性：系统评价和荟萃分析方案。
Efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of type 2 diabetes mellitus: A protocol for a systematic review and meta-analysis.
机构信息
Changchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.
Endocrinology, First Affiliated Hospital to Changchun University of Chinese Medicine, 1478 Gongnong Road, Changchun City, Jilin Province, China.
出版信息
Medicine (Baltimore). 2021 Oct 29;100(43):e27658. doi: 10.1097/MD.0000000000027658.
BACKGROUND
Diabetes has become a global public health problem and danger to human health. Diabetes is the main cause of blindness, kidney failure, heart attack, stroke, and lower limb amputation. According to the latest epidemiological survey and research, the overall prevalence of diabetes in mainland China is 11.2%, of which type 2 diabetes mellitus (T2DM) accounts for more than 90% acupuncture combined with Chinese herbal medicine have been widely used in the treatment of T2DM. However, we have not found a meta-analysis of their synergistic effects. Therefore, this systematic review and meta-analysis aims to evaluate the efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of T2DM.
METHOD
From inception up to September 20, 2021, the PubMed, Web of Science, Embase, AMED, Cochrane Library, CNKI, VIP, CBM, and Wanfang databases will be searched. The publication date or language will not be limited. We will apply a combination of medical keywords, including "acupuncture", "Chinese herbal medicine", and "type 2 diabetes mellitus". We will also check other ongoing and unpublished studies in the clinical trial registry. At the same time, we will manually search all reference lists from relevant systematic reviews to find other eligible studies. We will use Review Manager software (REVMAN v5.3 Cochrane Collaboration) to meta-analyze the selected literature. The study for acupuncture combined with Chinese herbal medicine in the treatment of T2DM was a randomized controlled study. Two researchers will independently review the research selection, data extraction, and research quality assessments. Finally, we will observe the outcome measures.
RESULTS
This study will generate evidence-based data on the treatment of T2DM with acupuncture combined with Chinese herbal medicine and will provide new ideas and treatment modalities to investigate in future research.
背景
糖尿病已成为全球性公共卫生问题和危害人类健康的主要因素。糖尿病是导致失明、肾衰竭、心脏病发作、中风和下肢截肢的主要原因。根据最新的流行病学调查和研究，中国大陆糖尿病的总体患病率为 11.2%，其中 2 型糖尿病（T2DM）占 90%以上。针灸联合中药已广泛应用于 T2DM 的治疗。然而，我们尚未发现关于其协同作用的荟萃分析。因此，本系统评价和荟萃分析旨在评估针灸联合中药治疗 T2DM 的疗效和安全性。
方法
从创建到 2021 年 9 月 20 日，我们将检索 PubMed、Web of Science、Embase、AMED、Cochrane Library、CNKI、VIP、CBM 和万方数据库。我们不会对出版日期或语言进行限制。我们将结合医学关键词（包括“针灸”、“中药”和“2 型糖尿病”）进行搜索。我们还将检查临床试验注册库中其他正在进行和未发表的研究。同时，我们将手动搜索所有相关系统评价的参考文献列表，以找到其他合格的研究。我们将使用 Review Manager 软件（REVMAN v5.3 Cochrane Collaboration）对选定文献进行荟萃分析。针灸联合中药治疗 T2DM 的研究是一项随机对照研究。两名研究人员将独立进行研究选择、数据提取和研究质量评估。最后，我们将观察结局指标。
结果
本研究将为针灸联合中药治疗 T2DM 提供循证数据，并为未来的研究提供新的思路和治疗方法。
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