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[凯尔血型不合所致胎儿成红细胞增多症]

[Fetal erythroblastosis in Kell incompatibility].

作者信息

Fuith L C, Bichler A, Schönitzer D

出版信息

Geburtshilfe Frauenheilkd. 1987 Feb;47(2):131-3. doi: 10.1055/s-2008-1035793.

Abstract

The case study reported here concerned an intrauterine death as a result of a Kell erythroblastosis. Allergization had been caused by the administration of Kell-positive banked blood. Irregular antibodies are on the increase as a result of the increasing number of blood transfusions. It is recommended that the Kell system be considered in the selection of banked blood for girls and women of childbearing age--a practice that has been followed at the Innsbruck University Clinics for almost four years now. The indirect Coombs' test should be performed in order to establish Kell antibodies and other clinically significant antibodies. The enzyme test is recommended as a supplementary examination, but should never be used as the sole antibody test. As with rhesus incompatibility, and insofar as the determination of the father's Kell characteristics show him to be an antigen carrier, monitoring of allergized pregnant women must be carried out with the help of antibody titer follow-ups, amniocenteses, and ultrasonographic examinations at short notice.

摘要

此处报告的案例研究涉及一例因凯尔母儿血型不合导致的宫内死亡。致敏是由于输注了凯尔阳性库存血引起的。由于输血次数的增加,不规则抗体的数量也在上升。建议在为育龄期女孩和妇女选择库存血时考虑凯尔血型系统——因斯布鲁克大学诊所已遵循这一做法近四年。应进行间接抗人球蛋白试验以检测凯尔抗体及其他具有临床意义的抗体。推荐酶试验作为补充检查,但绝不能将其用作唯一的抗体检测方法。与恒河猴血型不相容情况一样,只要确定父亲的凯尔血型特征表明其为抗原携带者,就必须借助抗体效价随访、羊膜穿刺术和超声检查,对致敏孕妇进行短期监测。

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