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神经网络模型能准确预测全膝关节翻修术后的出院去向吗?

Neural network models accurately predict discharge disposition after revision total knee arthroplasty?

机构信息

Bioengineering Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2022 Aug;30(8):2591-2599. doi: 10.1007/s00167-021-06778-3. Epub 2021 Oct 30.

Abstract

PURPOSE

Based on the rising incidence of revision total knee arthroplasty (TKA), bundled payment models may be applied to revision TKA in the near future. Facility discharge represents a significant cost factor for those bundled payment models; however, accurately predicting discharge disposition remains a clinical challenge. The purpose of this study was to develop and validate artificial intelligence algorithms to predict discharge disposition following revision total knee arthroplasty.

METHODS

A retrospective review of electronic patient records was conducted to identify patients who underwent revision total knee arthroplasty. Discharge disposition was defined as either home discharge or non-home discharge, which included rehabilitation and skilled nursing facilities. Four artificial intelligence algorithms were developed to predict this outcome and were assessed by discrimination, calibration and decision curve analysis.

RESULTS

A total of 2228 patients underwent revision TKA, of which 1405 patients (63.1%) were discharged home, whereas 823 patients (36.9%) were discharged to a non-home facility. The strongest predictors for non-home discharge following revision TKA were American Society of Anesthesiologist (ASA) score, Medicare insurance type and revision surgery for peri-prosthetic joint infection, non-white ethnicity and social status (living alone). The best performing artificial intelligence algorithm was the neural network model which achieved excellent performance across discrimination (AUC = 0.87), calibration and decision curve analysis.

CONCLUSION

This study developed four artificial intelligence algorithms for the prediction of non-home discharge disposition for patients following revision total knee arthroplasty. The study findings show excellent performance on discrimination, calibration and decision curve analysis for all four candidate algorithms. Therefore, these models have the potential to guide preoperative patient counselling and improve the value (clinical and functional outcomes divided by costs) of revision total knee arthroplasty patients.

LEVEL OF EVIDENCE

IV.

摘要

目的

基于翻修全膝关节置换术(TKA)发病率的上升,捆绑支付模式可能在不久的将来应用于翻修 TKA。对于这些捆绑支付模式来说,医疗机构的出院情况是一个重要的成本因素;然而,准确预测出院情况仍然是一个临床挑战。本研究旨在开发和验证人工智能算法,以预测翻修全膝关节置换术后的出院情况。

方法

对电子病历进行回顾性分析,以确定接受翻修全膝关节置换术的患者。出院情况定义为家庭出院或非家庭出院,包括康复和熟练护理机构。开发了四种人工智能算法来预测这一结果,并通过区分度、校准和决策曲线分析进行评估。

结果

共有 2228 名患者接受了翻修 TKA,其中 1405 名(63.1%)患者出院回家,823 名(36.9%)患者出院至非家庭医疗机构。翻修 TKA 后非家庭出院的最强预测因素是美国麻醉医师协会(ASA)评分、医疗保险类型和翻修手术治疗假体周围关节感染、非白种人种族和社会地位(独居)。表现最好的人工智能算法是神经网络模型,在区分度(AUC=0.87)、校准和决策曲线分析方面表现出色。

结论

本研究开发了四种人工智能算法,用于预测翻修全膝关节置换术后患者的非家庭出院情况。研究结果表明,所有四种候选算法在区分度、校准和决策曲线分析方面均表现出色。因此,这些模型有可能指导术前患者咨询,并提高翻修全膝关节置换术患者的价值(临床和功能结果除以成本)。

证据等级

IV。

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