Claydon Matthew H, Laggoune Jordan P, Wells-Quinn Thomas A, Malham Gregory M
Epworth Hospital, 89 Bridge Road, Richmond, Vic 3121, Melbourne, Australia; The Alfred Hospital, 55 Commercial Road, Prahran, Vic 3004, Melbourne, Australia.
Epworth Hospital, 89 Bridge Road, Richmond, Vic 3121, Melbourne, Australia.
Spine J. 2022 Mar;22(3):411-418. doi: 10.1016/j.spinee.2021.10.015. Epub 2021 Oct 27.
Anterior lumbar fusion surgery is increasing by an estimated 24% annually in the United States. There is a paucity of precise anatomic guidelines to help surgeons determine the appropriate anterior access incision site.
The purpose of this study is to compare the available anterior surface landmarks for the L4/L5 and L5/S1 disk levels to the disk levels determined by fluoroscopy, with the goal of creating a guide for surgical incision sites in anterior lumbar access surgery.
A prospective, observational cohort study of consecutive patients undergoing anterior lumbar spinal exposure for anterior lumbar interbody fusion (ALIF), total disk replacement (TDR), or a combination of the two procedures at levels L4/L5 and/or L5/S1.
All patients (n=183) undergoing primary ALIF and/or TDR surgery from June 2018 to April 2021 at the study sites were assessed for inclusion, and 18 patients were excluded. The remaining 165 patients were included in the study, and a total of 208 surgical levels were exposed.
Mean, standard deviation, and 95% confidence interval (CI) were calculated. At each level, the distance from the symphysis pubis to the target disk level (SD distance) and the distance from the symphysis pubis to the umbilicus (SU distance) were measured, and the SD/SU ratio was calculated. Paired 2-tailed t tests were used to assess significant differences (p<.05). An R (coefficient of determination) test was used to assess variability of the SD distance, SU distance, and SD/SU ratio at each level.
All physiologic and anatomic measures were collected prospectively by the investigators, including intraoperative measurements of SD and SU. Demographic and previous health history data were collected at the time of study enrollment.
The mean age of the 165 study participants was 48±14 years (range 18-80 years), and 97 (61%) were male. A total of 208 disk levels were exposed: 140 at L5/S1 and 68 at L4/L5. For the L5/S1, the SD ranged from 0 to 12.5 cm, with a mean of 5.2±1.9 cm (95% CI 4.88-5.52). For the L4/L5 level, the SD ranged from 6 to 15.5 cm, with a mean of 10.7±2.3 cm (95% CI 10.2-11.2). SD/SU ratios at both levels were lower in overweight (body mass index [BMI] 25-29.9) and obese (BMI 30-34.9) groups than in normal body mass index groups. There was no significant difference in SD/SU ratios between females and males at either L5/S1 (p=.39) or L4/L5 (p=.66).
Clinically important variability in SD distances (≥9.5 cm) was observed for both the L5/S1 and L4/L5 disk levels. SD/SU ratios provided more consistent estimates of disk location than SD distance alone, but they still displayed substantial variability. Thus, intraoperative fluoroscopy remains mandatory to accurately plan the surgical incision for anterior lumbar access surgery.
在美国,前路腰椎融合手术的年增长率估计为24%。目前缺乏精确的解剖学指南来帮助外科医生确定合适的前路手术切口位置。
本研究旨在比较L4/L5和L5/S1椎间盘水平的可用前表面标志与透视确定的椎间盘水平,目的是为前路腰椎手术的手术切口部位创建一个指南。
一项前瞻性观察队列研究,纳入连续接受前路腰椎椎间融合术(ALIF)、全椎间盘置换术(TDR)或两者联合手术的患者,手术节段为L4/L5和/或L5/S1。
2018年6月至2021年4月在研究地点接受初次ALIF和/或TDR手术的所有患者(n = 183)接受纳入评估,18例患者被排除。其余165例患者纳入研究,共暴露208个手术节段。
计算均值、标准差和95%置信区间(CI)。在每个节段,测量耻骨联合到目标椎间盘水平的距离(SD距离)和耻骨联合到脐的距离(SU距离),并计算SD/SU比值。采用配对双尾t检验评估显著差异(p < 0.05)。采用R(决定系数)检验评估每个节段SD距离、SU距离和SD/SU比值的变异性。
所有生理和解剖学测量均由研究人员前瞻性收集,包括术中SD和SU测量。在研究入组时收集人口统计学和既往健康史数据。
165例研究参与者的平均年龄为48±14岁(范围18 - 80岁),97例(61%)为男性。共暴露208个椎间盘节段:L5/S1节段140个,L4/L5节段68个。对于L5/S1节段,SD范围为0至12.5 cm,均值为5.2±1.9 cm(95%CI 4.88 - 5.52)。对于L4/L5节段,SD范围为6至15.5 cm,均值为10.7±2.3 cm(95%CI 10.2 - 11.2)。超重(体重指数[BMI] 25 - 29.9)和肥胖(BMI 30 - 34.9)组两个节段的SD/SU比值均低于正常体重指数组。L5/S1(p = 0.39)或L4/L5(p = 0.66)节段,女性和男性的SD/SU比值无显著差异。
在L5/S1和L4/L5椎间盘水平均观察到SD距离存在临床上重要的变异性(≥9.5 cm)。SD/SU比值比单独的SD距离能更一致地估计椎间盘位置,但仍显示出较大变异性。因此,前路腰椎手术中术中透视对于准确规划手术切口仍然是必需的。