Department for Rheumatology and Rehabilitation, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia,
Psychiatr Danub. 2021 Spring-Summer;33(Suppl 4):757-761.
The main benefits of cryotherapy in rheumatoid arthritis (RA) are in reducing inflammation and swelling and in relieving joint pain. This study aimed to compare the short-term effects of cold air therapy vs. ice massage, on pain and handgrip strength (HGS) in patients with RA.
The study is a non-randomized clinical trial. Patients were recruited if they had disease activity score (DAS28) ≥3.2 with at least 2 swollen joints on the dominant hand and were consecutively divided into two groups of 15 patients. There was no statistically significant difference in DAS28 score between groups. The first group received cold air therapy at -30°C and the second ice massage of the hands. The pain (visual analogue scale, 0-10), and HGS (kg) were measured immediately prior and after cryotherapy, and 30 and 60 minutes after cryotherapy. Descriptive statistics, Independent Samples T-test, and Paired Samples T-test were used for statistical analysis.
Pain intensities for cold air therapy were as follows: 5.33 (±2.44), 3.13 (±2.67), 2.87 (±2.56), 2.80 (±2.73), and for ice massage were: 5.20 (±2.37), 2.87 (±2.42), 2.60 (±2.23), 2.67 (±2.28). In both groups pain was significantly lower immediately after, 30 and 60 minutes after the treatment compared to the baseline (p=0.001). There was no significant difference in pain alleviation between the groups regarding the used method of cryotherapy on all three measured time points. Nonsignificant improvement in HGS occurred after both methods of cryotherapy. There was no significant correlation between pain intensity and HGS.
A single application of cold air therapy and ice massage equally provides immediate and significant pain alleviation in patients with active RA, which is maintained for one hour. There is scientific evidence that HGS is influenced greatly by the disease activity. A single application of cryotherapy could not reduce disease activity explaining recorded nonsignificant effect on HGS.
冷冻疗法在类风湿关节炎(RA)中的主要益处在于减轻炎症和肿胀,缓解关节疼痛。本研究旨在比较冷空气疗法与冰按摩对 RA 患者疼痛和握力(HGS)的短期影响。
这是一项非随机临床试验。如果患者疾病活动评分(DAS28)≥3.2,且优势手至少有 2 个肿胀关节,则将其纳入研究。两组患者的 DAS28 评分无统计学差异。第一组接受-30°C 的冷空气治疗,第二组接受手部冰按摩。治疗前、治疗后即刻、治疗后 30 分钟和 60 分钟时,分别测量疼痛(视觉模拟评分,0-10)和 HGS(kg)。采用描述性统计、独立样本 t 检验和配对样本 t 检验进行统计学分析。
冷空气治疗的疼痛强度分别为:5.33(±2.44)、3.13(±2.67)、2.87(±2.56)、2.80(±2.73),冰按摩的疼痛强度分别为:5.20(±2.37)、2.87(±2.42)、2.60(±2.23)、2.67(±2.28)。两组患者治疗后即刻、30 分钟和 60 分钟的疼痛均明显低于基线(p=0.001)。在所有三个测量时间点,两种冷冻疗法的疼痛缓解效果均无显著差异。两种冷冻疗法后 HGS 均有一定程度的改善,但无统计学意义。疼痛强度与 HGS 之间无显著相关性。
单次应用冷空气疗法和冰按摩均可立即显著缓解活动期 RA 患者的疼痛,这种缓解作用可维持 1 小时。有科学证据表明,HGS 受疾病活动度的影响很大。单次应用冷冻疗法不能降低疾病活动度,这可以解释其对 HGS 无显著影响。