Department of Neurology, Bozyaka Training and Research Hospital, Izmir, Turkey.
Department of Ophthalmology, İzmir Democracy Univesity, Güzelyalı Konak /İZMİR, Mehmet Ali Akman Mahallesi, 13. Sokak No:2, Izmir, Turkey.
Int Ophthalmol. 2022 Apr;42(4):1233-1239. doi: 10.1007/s10792-021-02109-0. Epub 2021 Oct 31.
We aimed to demonstrate the patient demographics, etiologies and apraclonidine test results in adult Horner's syndrome.
This retrospective study was performed by the analysis of medical data of patients who were given 0.5% apraclonidine test. Patients' past medical history, demographic data, etiologies, accompanying neurological findings and pharmacological test results were assessed.
Forty patients (21 females and 19 males) with a mean age of 50.3 ± 11.6 years were evaluated. Apraclonidine 0.5% test was positive in 37 patients (92.5%). An etiology could be identified in 20 patients (central [9 patients, 45%], preganglionic [9 patients, 45%] and postganglionic [2 patients, 10%]). Neurological findings accompanying Horner's syndrome were present in 8 patients.
Despite detailed investigations, in a significant number of patients with Horner's syndrome an underlying cause may not be detected. Among the identifiable lesions, central and preganglionic involvements are still the first leading causes of Horner's syndrome. In addition, apraclonidine test may not be positive in all patients and a negative response does not exclude Horner's syndrome.
我们旨在展示成人霍纳综合征患者的人口统计学、病因和可乐定试验结果。
通过对接受 0.5%可乐定试验的患者的医学数据进行分析，进行了这项回顾性研究。评估了患者的既往病史、人口统计学数据、病因、伴随的神经学发现和药物学试验结果。
40 名患者（21 名女性和 19 名男性），平均年龄为 50.3±11.6 岁。37 名患者（92.5%）可乐定 0.5%试验阳性。20 名患者（中枢性[9 例，45%]、节前性[9 例，45%]和节后性[2 例，10%]）可以确定病因。8 名霍纳综合征患者伴有神经学发现。
尽管进行了详细的调查，但在相当数量的霍纳综合征患者中，可能无法发现潜在的病因。在可识别的病变中，中枢性和节前性仍是霍纳综合征的首要原因。此外，并非所有患者的可乐定试验都呈阳性，阴性反应并不能排除霍纳综合征。
