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“继续服用,继续希望它们有效”:一项关于坚持治疗多种疾病药物的定性研究。

'Just keep taking them, keep hoping they'll work': A qualitative study of adhering to medications for multimorbidity.

机构信息

School of Psychology, National University of Ireland Galway, Ireland.

Croí Heart and Stroke Centre, Galway, Ireland.

出版信息

Br J Health Psychol. 2022 Sep;27(3):691-715. doi: 10.1111/bjhp.12568. Epub 2021 Oct 31.

Abstract

OBJECTIVE

Compared to single diseases, health psychology reflects many areas of medical research by affording relatively less attention to the experiences of people self-managing multiple co-occurring conditions and, in particular, the experience of managing the associated complex medication regimens. This study aimed to explore the experience of self-managing multimorbidity among older adults, with a focus on medication adherence.

DESIGN

A qualitative approach was taken, using individual semi-structured interviews.

METHODS

Sixteen people with complex multimorbidity aged 65 years or older were recruited through general practice to take part in semi-structured interviews. Data were analysed following guidelines for reflexive thematic analysis.

RESULTS

Two themes were generated, with each theme comprising three subthemes. Theme one represents the amplified burden arising from multimorbidity that leads to unique challenges for self-management, such as integrating multiple medications into daily life, accumulating new symptoms and treatments, and managing evolving medication regimens. Theme two represents pathways towards relief that reduce this burden and promote medication adherence, such as prioritising certain conditions and treatments, resigning to the need for multiple medications, and identifying and utilising adherence supports.

CONCLUSIONS

We identified factors relevant to medication adherence for older adults with multimorbidity that go beyond single-disease influences and account for the amplified experience of chronic disease that multimorbidity can produce for some people. While evidence of single-disease influences remains fundamental to tailoring behavioural interventions to individuals, the impact of multimorbidity on medication adherence should be accounted for in research and practice.

摘要

目的

与单一疾病相比,健康心理学通过较少关注自我管理多种共病的人群的体验,特别是管理相关复杂药物治疗方案的体验,反映了许多医学研究领域。本研究旨在探讨老年人自我管理多种共病的体验,重点是药物依从性。

设计

采用定性方法,使用个体半结构化访谈。

方法

通过普通实践招募了 16 名年龄在 65 岁或以上、患有复杂多种共病的人参加半结构化访谈。数据按照反思性主题分析指南进行分析。

结果

生成了两个主题,每个主题包含三个子主题。主题一代表了多种共病带来的放大负担,导致自我管理面临独特的挑战,例如将多种药物融入日常生活、积累新的症状和治疗方法以及管理不断变化的药物治疗方案。主题二代表了减轻这种负担并促进药物依从性的途径,例如优先考虑某些疾病和治疗方法、接受需要多种药物的现实以及识别和利用依从性支持。

结论

我们确定了与多种共病老年人药物依从性相关的因素,这些因素超出了单一疾病的影响,并解释了多种共病对某些人产生的慢性疾病体验的放大。虽然单疾病影响的证据仍然是为个体定制行为干预的基础,但应在研究和实践中考虑多种共病对药物依从性的影响。

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