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[自闭症谱系障碍儿童的营养状况及营养特点]

[Features of the nutritional status and nutrition of children with autistic disorders].

作者信息

Tkachuk E A, Martynovich N N, Globenko N E

机构信息

Irkutsk State Medical University, Ministry of Health of the Russian Federation, 664003, Irkutsk, Russian Federation.

Research Center for Family Health and Human Reproduction Problems, 664003, Irkutsk, Russian Federation.

出版信息

Vopr Pitan. 2021;90(5):67-76. doi: 10.33029/0042-8833-2021-90-5-67-76. Epub 2021 Sep 1.

Abstract

In recent years, there has been a steady increase in the number of children with autism spectrum disorders (ASD). According to the Ministry of Health of Russia, the incidence of ASD in children under 2 years of age is 5:10 000, at the age of 4 years - 18:10 000. ASD is a complex multisystem disease that affects metabolic and neurobiological processes. of the research was to analyze the dietary habits of children with autism spectrum disorders. In ASD, physical developmental disorders occur, both in the direction of increasing and decreasing body weight, which is accompanied by pathology of the gastrointestinal tract (GIT) and eating disorders. Diseases of the digestive system are associated with both inflammatory and functional disorders in the GIT, changes in the immune status, autonomic tone of the nervous system and the composition of the GIT microbiota. Eating disorders in children with ASD lead to negative changes in the child's nutritional status and aggravates the course of gastrointestinal diseases. Nutritional status in children with ASD is characterized by an excess of calories in the diet (or a sharp decrease in it), excessive consumption of fat, sugar and salt, deficiency of vitamins, carotenoids, mineral substances (calcium in 45.1%, lithium in 30-35%, potassium in 70% of children with ASD). It has been found that nutritional deficiencies in ASD exacerbate neuropsychiatric symptoms. Lack of vitamins leads to metabolic disorders, delayed physical and mental development, rapid fatigue, endocrine dysfunction, and aggravation of the symptoms of ASD. . Nutritional adjustments in children with ASD can lead to an improvement in non-verbal IQ and a decrease in the clinical manifestations of autism. The issue of developing recommendations for the organization of nutrition for children with ASD in educational institutions remains highly relevant.

摘要

近年来,自闭症谱系障碍(ASD)儿童的数量一直在稳步增加。根据俄罗斯卫生部的数据,2岁以下儿童的ASD发病率为5:10000,4岁儿童为18:10000。ASD是一种复杂的多系统疾病,会影响代谢和神经生物学过程。本研究的目的是分析自闭症谱系障碍儿童的饮食习惯。在ASD中,身体发育障碍会出现,体重有增加和减少两个方向的变化,同时伴有胃肠道(GIT)疾病和饮食失调。消化系统疾病与GIT中的炎症和功能障碍、免疫状态变化、神经系统自主神经张力以及GIT微生物群的组成有关。ASD儿童的饮食失调会导致儿童营养状况的负面变化,并加重胃肠道疾病的病程。ASD儿童的营养状况表现为饮食中热量过多(或急剧减少)、脂肪、糖和盐的过量摄入、维生素、类胡萝卜素、矿物质缺乏(45.1%的ASD儿童缺钙,30 - 35%缺锂,70%缺钾)。研究发现,ASD中的营养缺乏会加重神经精神症状。缺乏维生素会导致代谢紊乱、身心发育迟缓、快速疲劳、内分泌功能障碍以及ASD症状加重。对ASD儿童进行营养调整可以提高非语言智商,并减少自闭症的临床表现。在教育机构中为ASD儿童制定营养建议的问题仍然高度相关。

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