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COVID-19 肺炎合并急性胃黏膜病变出血一例罕见。

A Rare Case of COVID-19 Pneumonia Concomitant with Bleeding from Acute Gastric Mucosal Lesions.

机构信息

Department of Gastroenterology, Kyoto Okamoto Memorial Hospital, Japan.

Department of Pathology, Kyoto Okamoto Memorial Hospital, Japan.

出版信息

Intern Med. 2021;60(21):3421-3426. doi: 10.2169/internalmedicine.7803-21. Epub 2021 Nov 1.

Abstract

A 70-year-old man was diagnosed with coronavirus disease 2019 (COVID-19) pneumonia. Twenty-six days after admission, he experienced hematemesis despite improvement in his respiratory symptoms. Contrast-enhanced computed tomography revealed edematous stomach wall thickening with neither ischemic findings in the gastric wall nor obstruction of the gastric artery. Emergent esophagogastroduodenoscopy showed diffuse dark-red mucosa accompanied by multiple easy-bleeding, irregularly shaped ulcers throughout almost the whole stomach without active bleeding or visible vessels. The clinical course, including the endoscopic findings, progressed favorably with conservative treatment. COVID-19 pneumonia can present with acute gastric mucosal lesion, which may be induced by microvascular thrombosis due to COVID-19-related coagulopathy.

摘要

一位 70 岁男性被诊断患有 2019 冠状病毒病(COVID-19)肺炎。入院 26 天后,尽管呼吸症状有所改善,但他出现了咯血。增强 CT 显示胃壁水肿性增厚,胃壁无缺血表现,胃动脉无阻塞。紧急食管胃十二指肠镜检查显示弥漫性暗红色黏膜,伴有多处易出血、形状不规则的溃疡,几乎遍布整个胃,但无活动性出血或可见血管。临床过程包括内镜检查结果,经保守治疗后顺利好转。COVID-19 肺炎可表现为急性胃黏膜病变,这可能是由 COVID-19 相关凝血功能障碍引起的微血管血栓形成所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0e5/8627797/1791ad28000d/1349-7235-60-3421-g001.jpg

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