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产前诊断及多学科管理:先天性颗粒细胞瘤 1 例报告并文献复习

Prenatal diagnosis and multidisciplinary management: a case report of congenital granular cell epulis and literature review.

机构信息

Children's Health Centre, Sichuan Provincial Maternity and Child Health Care Hospital, Chengdu, Sichuan Province, China.

Department of Neonatology, Sichuan Provincial Maternity and Child Health Care Hospital, Chengdu, Sichuan Province, China.

出版信息

J Int Med Res. 2021 Oct;49(10):3000605211053769. doi: 10.1177/03000605211053769.

DOI:10.1177/03000605211053769
PMID:34719988
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8562647/
Abstract

Congenital granular cell epulis (CGCE) is a rare benign soft tissue lesion that usually originates from the neonatal gingiva and can lead to difficulty in breathing and feeding upon birth. This current case report describes a female newborn with a gingival mass that was identified by prenatal fetal ultrasonography. At birth, the oral mass was observed to protrude from the mouth, which adversely affected feeding. The lips could not be closed. The breathing was unaffected. Through a multidisciplinary team approach involving several healthcare professionals, the mass was successfully removed under general anaesthesia during an uncomplicated surgical procedure. Postoperative histopathological examination confirmed that the mass was a CGCE of the newborn. The infant recovered well after the operation.

摘要

先天性颗粒细胞瘤性龈瘤(CGCE)是一种罕见的良性软组织病变,通常起源于新生儿的牙龈,并可能导致出生时呼吸困难和喂养困难。本病例报告描述了一名女性新生儿,其牙龈肿块通过产前胎儿超声检查发现。出生时,口腔肿块从口腔突出,这对喂养产生了不利影响。嘴唇无法闭合。呼吸不受影响。通过涉及多名医疗保健专业人员的多学科团队方法,在简单的手术过程中,在全身麻醉下成功切除了肿块。术后组织病理学检查证实肿块为新生儿 CGCE。手术后婴儿恢复良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/6ccfe0b99ac0/10.1177_03000605211053769-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/e4b85c6b58bb/10.1177_03000605211053769-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/094e62017855/10.1177_03000605211053769-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/762a28c6bbf9/10.1177_03000605211053769-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/6ccfe0b99ac0/10.1177_03000605211053769-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/e4b85c6b58bb/10.1177_03000605211053769-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/094e62017855/10.1177_03000605211053769-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/762a28c6bbf9/10.1177_03000605211053769-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/039c/8562647/6ccfe0b99ac0/10.1177_03000605211053769-fig4.jpg

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本文引用的文献

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Congenital Granular Cell Epulis: Classic Presentation and Its Differential Diagnosis.先天性颗粒细胞瘤:典型表现及其鉴别诊断。
Head Neck Pathol. 2020 Mar;14(1):208-211. doi: 10.1007/s12105-019-01025-1. Epub 2019 Mar 19.
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Congenital Epulis: A Case and Review of the Literature.先天性龈瘤:病例报告及文献综述
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Two variations of congenital epulis.先天性龈瘤的两种变异型。
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Congenital granular cell tumor - a rare entity.先天性颗粒细胞瘤——一种罕见的实体。
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Histogenesis and clinical analysis of 2 cases of congenital gingival granular cell tumour.2例先天性牙龈颗粒细胞瘤的组织发生及临床分析
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The CARE guidelines: consensus-based clinical case reporting guideline development.CARE 指南:基于共识的临床病例报告指南制定。
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Congenital epulis.先天性龈瘤
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Prenatal diagnosis of congenital epulis by 2D/3D ultrasound and magnetic resonance.二维/三维超声及磁共振对先天性龈瘤的产前诊断。
Fetal Diagn Ther. 2013;33(4):272-6. doi: 10.1159/000346811. Epub 2013 Mar 19.