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肝动脉灌注化疗是肝细胞癌的一种可行治疗选择:最新进展

Hepatic Arterial Infusion Chemotherapy Is a Feasible Treatment Option for Hepatocellular Carcinoma: A New Update.

作者信息

Hendi Maher, Mou Yiping, Lv Jiemin, Zhang Bin, Cai Xiujun

机构信息

Department of Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Department of Surgery, Zhejiang Provincial Peoples Hospital, Hangzhou, China.

出版信息

Gastrointest Tumors. 2021 Jul 15;8(4):145-152. doi: 10.1159/000516405. eCollection 2021 Oct.

Abstract

BACKGROUND

Hepatic arterial infusion chemotherapy (HAIC) is one option for treating massive tumors and unresectable hepatocellular carcinoma (HCC). However, there is a lack of remedial treatment after these treatments are ineffective or failed.

SUMMARY

Some studies have discovered that HAIC has greater survival in patients with advanced HCC. A previous study has shown that HAIC is effective in the treatment of advanced HCC, and the data on randomized clinical trials are limited and unclear.

KEY MESSAGE

More clinical trials and research are needed in order to make HAIC a standard and recommended therapy for advanced HCC. Our review focuses on the clinical applications of hepatic artery infusion treatment.

摘要

背景

肝动脉灌注化疗(HAIC)是治疗巨大肿瘤和不可切除肝细胞癌(HCC)的一种选择。然而,这些治疗无效或失败后缺乏补救治疗。

总结

一些研究发现,HAIC对晚期HCC患者有更高的生存率。先前的一项研究表明,HAIC在晚期HCC治疗中有效,而随机临床试验的数据有限且不明确。

关键信息

为了使HAIC成为晚期HCC的标准和推荐疗法,需要更多的临床试验和研究。我们的综述重点关注肝动脉灌注治疗的临床应用。

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