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手机电磁辐射对小鼠记忆或焦虑无显著影响:对创伤性脑损伤小鼠有一些混合效应。

No Significant Effects of Cellphone Electromagnetic Radiation on Mice Memory or Anxiety: Some Mixed Effects on Traumatic Brain Injured Mice.

作者信息

Qubty Doaa, Schreiber Shaul, Rubovitch Vardit, Boag Amir, Pick Chaim G

机构信息

Department of Anatomy and Anthropology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Department of Psychiatry, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

出版信息

Neurotrauma Rep. 2021 Aug 17;2(1):381-390. doi: 10.1089/neur.2021.0009. eCollection 2021.

Abstract

Current literature details an array of contradictory results regarding the effect of radiofrequency electromagnetic radiation (RF-EMR) on health, both in humans and in animal models. The present study was designed to ascertain the conflicting data published regarding the possible impact of cellular exposure (radiation) on male and female mice as far as spatial memory, anxiety, and general well-being is concerned. To increase the likelihood of identifying possible "subtle" effects, we chose to test it in already cognitively impaired (following mild traumatic brain injury; mTBI) mice. Exposure to cellular radiation by itself had no significant impact on anxiety levels or spatial/visual memory in mice. When examining the dual impact of mTBI and cellular radiation on anxiety, no differences were found in the anxiety-like behavior as seen at the elevated plus maze (EPM). When exposed to both mTBI and cellular radiation, our results show improvement of visual memory impairment in both female and male mice, but worsening of the spatial memory of female mice. These results do not allow for a decisive conclusion regarding the possible hazards of cellular radiation on brain function in mice, and the mTBI did not facilitate identification of subtle effects by augmenting them.

摘要

当前文献详细阐述了一系列关于射频电磁辐射(RF-EMR)对人类和动物模型健康影响的相互矛盾的结果。本研究旨在确定已发表的关于细胞暴露(辐射)对雄性和雌性小鼠空间记忆、焦虑和总体健康可能影响的相互矛盾的数据。为了增加识别可能的“细微”影响的可能性,我们选择在已经存在认知障碍(轻度创伤性脑损伤后;mTBI)的小鼠中进行测试。细胞辐射本身对小鼠的焦虑水平或空间/视觉记忆没有显著影响。在研究mTBI和细胞辐射对焦虑的双重影响时,在高架十字迷宫(EPM)中观察到的焦虑样行为没有差异。当同时暴露于mTBI和细胞辐射时,我们的结果显示,雄性和雌性小鼠的视觉记忆损伤均有改善,但雌性小鼠的空间记忆恶化。这些结果无法就细胞辐射对小鼠脑功能的潜在危害得出决定性结论,并且mTBI并没有通过增强这些影响来促进对细微影响的识别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d4a/8550818/f9e8065f95ea/neur.2021.0009_figure1.jpg

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