Temporary threshold shift induced by noise exposure and moderate salicylate intake.

Temporary threshold shift was examined in 10 voluntary subjects who were exposed on 5 occasions to noise only and on 5 additional occasions to noise after intake of 1 g acetylsalicylic acid (ASA). The results showed no evidence that moderate doses of ASA potentiate temporary threshold shift. Subjects tested before and 1 hour after intake of ASA showed hearing improvement after intake of ASA. This threshold shift was confirmed, by a control trial, to depend on a practice effect rather than on the ASA.