Department of Surgery, Barwon Health, Surgery, University Hospital Geelong, Bellarine Street, University Hospital Geelong, Geelong, Victoria, Australia.
Department of Surgery, Barwon Health, Surgery, Geelong, Victoria, Australia.
ANZ J Surg. 2022 Jun;92(6):1377-1381. doi: 10.1111/ans.17334. Epub 2021 Nov 1.
Assessment scales are commonly used to diagnose and treat alcohol withdrawal syndrome (AWS) in acute hospitals, although they have only been validated for use in detoxification facilities. There is a significant overlap between the symptoms and signs of AWS and other clinical presentations, including systemic inflammatory response syndrome (SIRS) and the physiological response to surgery. This may lead to both over-diagnosis and inappropriate treatment of AWS. This study sought to determine the false-positive rate for the commonly used Clinical Institute Withdrawal Assessment for Alcohol-Revised (CIWA-Ar) among post-operative patients.
This was a prospective study of patients undergoing major abdominal surgery at University Hospital Geelong. Patients were recruited who were NOT at risk of alcohol dependency (using the World Health Organisation Alcohol Use Disorders Identification Test). Patients were assessed for AWS using the CIWA-Ar day one post-operatively with a false positive measured as a CIWA-Ar > 7.
A total of 67 patients were included in the study. There were 31 (46%) men and 36 women. Their median age was 52 years (range 27-85). Thirty-six (52%) of patients underwent elective procedures, and 32 were emergencies. Twelve of the 67 patients (18%) had CIWA-Ar scores >seven.
In the early post-operative period, the CIWA-Ar tool over-diagnoses AWS in 18% of patients. These false-positives could lead to delayed treatment of serious underlying conditions. We call for caution in the use of alcohol withdrawal scales in the acute hospital setting.
评估量表常用于急性医院中诊断和治疗酒精戒断综合征(AWS),尽管它们仅在戒毒机构中经过验证可以使用。AWS 的症状和体征与其他临床表现(包括全身炎症反应综合征(SIRS)和手术的生理反应)有很大的重叠。这可能导致 AWS 的过度诊断和不适当治疗。本研究旨在确定常用于术后患者的临床戒断评估酒精修订版(CIWA-Ar)的假阳性率。
这是对在澳大利亚维多利亚州吉隆大学医院接受大腹部手术的患者进行的前瞻性研究。招募了没有酒精依赖风险的患者(使用世界卫生组织酒精使用障碍识别测试)。术后第一天使用 CIWA-Ar 对 AWS 进行评估,假阳性定义为 CIWA-Ar>7。
共有 67 名患者纳入研究。其中 31 名(46%)为男性,36 名为女性。他们的中位年龄为 52 岁(范围 27-85 岁)。36 名(52%)患者接受了择期手术,32 名是急诊。在 67 名患者中,有 12 名(18%)的 CIWA-Ar 评分>7。
在术后早期,CIWA-Ar 工具会过度诊断 18%的 AWS 患者。这些假阳性可能导致严重潜在疾病的治疗延迟。我们呼吁在急性医院环境中使用酒精戒断量表时要谨慎。